Characteristics associated with quality of life among people with drug-resistant epilepsy
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DOI: 10.1007/s00415-017-8512-1
Abstract: Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among… read more here.
Keywords: epilepsy; associated quality; quality life; qol ... See more keywords
ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.082
Abstract: Ribosome-associated quality control (RQC) disassembles aberrantly stalled translation complexes to recycle or degrade the constituent parts. A key step of RQC is the cleavage of P-site tRNA by the endonuclease ANKZF1 (Vms1 in yeast) to… read more here.
Keywords: associated quality; quality control; elac1 repairs; ribosome associated ... See more keywords
Ribosome-associated quality-control mechanisms from bacteria to humans.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cell"
DOI: 10.1016/j.molcel.2022.03.038
Abstract: Ribosome-associated quality-control (RQC) surveys incomplete nascent polypeptides produced by interrupted translation. Central players in RQC are the human ribosome- and tRNA-binding protein, NEMF, and its orthologs, yeast Rqc2 and bacterial RqcH, which sense large ribosomal… read more here.
Keywords: associated quality; quality control; nascent chain; ribosome associated ... See more keywords
Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society transactions"
DOI: 10.1042/bst20220549
Abstract: Maintenance of proteostasis is of utmost importance to cellular viability and relies on the coordination of many post-transcriptional processes to respond to stressful stimuli. Stress granules (SGs) are RNA-protein condensates that form after translation initiation… read more here.
Keywords: rqc pathway; stress; quality control; associated quality ... See more keywords
Factors Associated with the Quality and Transparency of National Guidelines: A Mixed-Methods Study
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DOI: 10.3390/ijerph19159515
Abstract: We assessed the methodological quality and transparency of all the national clinical practice guidelines that were published in Croatia up until 2017 and explored the factors associated with their quality rating. An in-depth quantitative and… read more here.
Keywords: transparency national; quality; methodology; quality transparency ... See more keywords
Comprehensive Multimorbidity Patterns in Older Patients Are Associated with Quality Indicators of Medication—MoPIM Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192315902
Abstract: Multimorbidity is increasing and poses a challenge to the clinical management of patients with multiple conditions and drug prescriptions. The objectives of this work are to evaluate if multimorbidity patterns are associated with quality indicators… read more here.
Keywords: multimorbidity patterns; indicators medication; quality indicators; associated quality ... See more keywords