Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
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DOI: 10.1111/acel.12682
Abstract: Sirtuin 2 (SIRT2) is a member of a family of NAD+‐dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for aging process. SIRT2 is located in the nucleus, cytoplasm, and mitochondria,… read more here.
Keywords: locomotor; energy; sirt2; associated redox ... See more keywords