The microtubule-associated RING finger protein 1 (OsMAR1) acts as a negative regulator for salt-stress response through the regulation of OCPI2 (O. sativa chymotrypsin protease inhibitor 2)
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DOI: 10.1007/s00425-017-2834-1
Abstract: Main conclusionOur results suggest that a rice E3 ligase, OsMAR1, physically interacts with a cytosolic protein OCPI2 and may play an important role under salinity stress.Salt is an important abiotic stressor that negatively affects plant… read more here.
Keywords: protein; associated ring; response; microtubule associated ... See more keywords
Up-regulation of BRCA1-associated RING Domain 1 Promotes Hepatocellular Carcinoma Progression by Targeting Akt Signaling
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DOI: 10.1038/s41598-017-07962-7
Abstract: The present study was designed to investigate the potential clinical, pathological, prognostic value, role and mechanism of BRCA1-associated RING Domain 1 (BARD1) in Hepatocellular carcinoma (HCC). Quantitative real-time PCR and immunohistochemistry were performed to evaluate… read more here.
Keywords: associated ring; hcc; bard1; ring domain ... See more keywords
HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1(BARD1) Isoforms
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DOI: 10.3390/cancers14071848
Abstract: Simple Summary RNA binding proteins (RBPs) post-transcriptionally regulate and stabilize a variety of target mRNA transcripts. Human Antigen R (HuR) binds to several pro-survival mRNA transcripts and promotes tumor cell survival and chemotherapeutic resistance. Some… read more here.
Keywords: pdac; associated ring; hur; ring domain ... See more keywords