A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01942-1
Abstract: Detection of extracellular vesicle (EV)-associated RNAs with low expression levels in early-stage cancer remains a challenge and is highly valuable. Here, we report a nanoparticle-based biochip that could capture circulating EVs without isolation, brighten encapsulated… read more here.
Keywords: rnas early; extracellular vesicle; early cancer; vesicle associated ... See more keywords
A new chemical approach for proximity labelling of chromatin-associated RNAs and proteins with visible light irradiation.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc06251c
Abstract: A new nucleus-localized singlet oxygen generator was designed and synthesized. Its capability to label nucleus-localized biomolecules through spatially-restricted oxidation under visible light was validated using fluorescence confocal microscopy. Western blot and RT-qPCR were performed to… read more here.
Keywords: new chemical; visible light; chromatin associated; associated rnas ... See more keywords
Classification of Transcription Boundary-Associated RNAs (TBARs) in Animals and Plants
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00168
Abstract: There is increasing evidence suggesting the contribution of non-coding RNAs (ncRNAs) to the phenotypic and physiological complexity of organisms. A novel ncRNA species has been identified near the transcription boundaries of protein-coding genes in eukaryotes,… read more here.
Keywords: transcription; classification; transcription boundary; boundary associated ... See more keywords
Surveillance of Tumour Development: The Relationship Between Tumour-Associated RNAs and Ribonucleases
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01019
Abstract: Tumour progression is accompanied by rapid cell proliferation, loss of differentiation, the reprogramming of energy metabolism, loss of adhesion, escape of immune surveillance, induction of angiogenesis, and metastasis. Both coding and regulatory RNAs expressed by… read more here.
Keywords: tumour development; tumour associated; development relationship; surveillance tumour ... See more keywords