Genome-wide identification of m6A-associated single-nucleotide polymorphisms in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.135315
Abstract: N6-methyladenosine (m6A)-associated single nucleotide polymorphisms (SNPs) play a vital role in several neurological diseases. However, little is known about the relationship between m6A modification and Parkinson's disease (PD). We investigated potential functional variants of m6A-SNPs… read more here.
Keywords: nucleotide polymorphisms; single nucleotide; m6a associated; m6a snps ... See more keywords
Analyzing Change in Protein Stability Associated with Single Point Deletions in a Newly Defined Protein Structure Database.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00048
Abstract: Protein backbone alternation due to insertion/deletion or mutation operation often results in a change of fundamental biophysical properties of proteins. The proposed work intends to encode the protein stability changes associated with single point deletions… read more here.
Keywords: protein; point deletions; protein stability; database ... See more keywords
Risk‐associated single nucleotide polymorphisms of mitochondrial D‐loop mediate imbalance of cytokines and redox in rheumatoid arthritis
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DOI: 10.1111/1756-185x.14465
Abstract: We have identified rheumatoid arthritis (RA) risk‐associated single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D‐loop) including the major alleles of nucleotides 195T/C, 16260C/T, and 16519C/T as well as the minor alleles of nucleotides… read more here.
Keywords: loop; nucleotide polymorphisms; rheumatoid arthritis; single nucleotide ... See more keywords
Factors Associated with Single-Use and Co-Use of Tobacco and Alcohol: A Multinomial Modeling Approach
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DOI: 10.3390/ijerph16193506
Abstract: Tobacco smoking and alcohol consumption are among the most important public health concerns not only in South Korea but also globally. This study identified the factors associated with single-use and co-use of tobacco and alcohol… read more here.
Keywords: tobacco; use; group; factors associated ... See more keywords