Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.44425
Abstract: Unfolded protein responses (UPRs) safeguard cellular function during proteotoxic stress and aging. In a previous paper (Lehrbach and Ruvkun, 2016) we showed that the ER-associated SKN-1A/Nrf1 transcription factor activates proteasome subunit expression in response to… read more here.
Keywords: endoplasmic reticulum; response; unfolded protein; skn nrf1 ... See more keywords