A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-018-0297-x
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disorder with heterogeneous clinical presentation and complex etiology involving the interplay between genetic, epigenetic, environmental and hormonal factors. Many common SNPs identified by genome wide-association studies (GWAS) explain… read more here.
Keywords: rare regulatory; regulatory variant; variant; associated sle ... See more keywords
Systemic lupus erythematosus and toll-like receptor 9 polymorphisms: A meta-analysis of genetic association studies.
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DOI: 10.1177/09612033231180695
Abstract: OBJECTIVE This study aimed to examine whether polymorphisms in toll-like receptor 9 (TLR9) contribute to vulnerability to systemic lupus erythematosus (SLE). METHODS We searched the MEDLINE, Embase, and Web of Science databases for relevant articles.… read more here.
Keywords: meta analysis; associated sle; analysis; association ... See more keywords