Germline variation in the 3′‐untranslated region of the POU2AF1 gene is associated with susceptibility to lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22652
Abstract: Genetic variations in certain genes may alter the susceptibility to lymphoma. We searched electronic databases and selected candidate single‐nucleotide polymorphisms (SNPs) located within 3′‐untranslated regions (3′‐UTRs) that might affect miRNA‐binding ability in the 50 most… read more here.
Keywords: lymphoma; susceptibility lymphoma; pou2af1; lymphoma 001 ... See more keywords
Interleukin-21 receptor gene polymorphism (rs2285452 A/G) is associated with susceptibility to Behçet's disease.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of immunogenetics"
DOI: 10.1111/iji.12623
Abstract: Behçet's disease (BD) is a chronic auto inflammatory disorder of unknown aetiology. Recently, the dysregulation of interleukin-21 receptor (IL-21R) has been incriminated in different autoimmune and auto-inflammatory diseases, such as systemic lupus erythematous, rheumatoid arthritis,… read more here.
Keywords: 21r rs2214537; 21r rs2285452; beh disease; associated susceptibility ... See more keywords
Interleukin‐10 promoter variability is associated with the susceptibility, severity, and clinical outcomes of aplasitc anemia in Han‐Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13993
Abstract: Acquired aplastic anemia (AA), a heterogeneous bone marrow (BM) failure disease, is mainly mediated by the immune destruction of hematopoietic stem cells (HSCs). Given the predominant role of immunosuppressive therapy (IST) in AA, it is… read more here.
Keywords: associated susceptibility; interleukin promoter; severity clinical; variability associated ... See more keywords
Polymorphisms in the Osteopontin Are Associated with Susceptibility to Ankylosing Spondylitis in a Han Chinese Population
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3458439
Abstract: The aim of this study was to investigate whether osteopontin (OPN) variants are associated with susceptibility to ankylosing spondylitis (AS) in a Chinese population. Polymorphisms at the 9175th position in exon 7 of OPN and… read more here.
Keywords: susceptibility; ankylosing spondylitis; susceptibility ankylosing; chinese population ... See more keywords
Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007458
Abstract: Chronic inflammation in inflammatory bowel disease (IBD) results from a breakdown of intestinal immune homeostasis and compromise of the intestinal barrier. Genome-wide association studies have identified over 200 genetic loci associated with risk for IBD,… read more here.
Keywords: bowel disease; inflammatory bowel; expression; tnfsf15 ... See more keywords
Susceptibility to smoking and determinants among medical students: A representative nationwide study in China
Sign Up to like & getrecommendations! Published in 2019 at "Tobacco Induced Diseases"
DOI: 10.18332/tid/106188
Abstract: INTRODUCTION The rationale behind why the majority of medical students are non-smokers, but some initiate smoking after becoming physicians is not fully understood in China. Exploring factors that may increase susceptibility to smoking initiation among… read more here.
Keywords: among medical; medical students; susceptibility; susceptibility smoking ... See more keywords
TBX5 Variants are Associated with Susceptibility to and the Incidence of Liver Cirrhosis and Hepatocellular Carcinoma in the Chinese Population: A Multicenter and Follow-Up Study
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s410151
Abstract: Purpose Liver cirrhosis (LC) and hepatocellular carcinoma (HCC) are progressions affected by genetic predispositions, and persistent hepatitis B virus infection also demonstrates genetic susceptibility. All HBV-related outcomes have been compared in parallel to identify risk… read more here.
Keywords: hepatocellular carcinoma; liver cirrhosis; infection; cirrhosis hepatocellular ... See more keywords
Novel Functional eQTL-SNPs Associated With Susceptibility to Mycoplasma pneumoniae Pneumonia in Children
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.899045
Abstract: Background The functional causal single-nucleotide polymorphisms (SNPs) associated with susceptibility to Mycoplasma pneumoniae Pneumonia (MPP) have scarcely been identified. In this study, we aimed to analyze the association between the functional expression quantitative trait locus… read more here.
Keywords: functional eqtl; associated susceptibility; eqtl snps; snps ... See more keywords
Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v23.i29.5364
Abstract: AIM To investigate whether single nucleotide polymorphisms in maf protein K (MAFK), which encodes the MAFK, lead to increased susceptibility to ulcerative colitis in the Japanese population. METHODS This case control study examined the associations… read more here.
Keywords: susceptibility ulcerative; susceptibility; maf protein; ulcerative colitis ... See more keywords