Transplant‐associated thrombotic microangiopathy: an unresolved complication of unrelated allogeneic transplant for hematologic diseases
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2346
Abstract: We read with great interest the study by Ye and colleagues regarding risk factors and prognosis of transplant‐associated thrombotic microangiopathy (TA‐TMA). Indeed, TA‐TMA represents a devastating and life‐threatening complication occurring more frequently in allogeneic compared… read more here.
Keywords: associated thrombotic; transplant associated; complication; transplant ... See more keywords
HIV‐associated thrombotic thrombocytopaenic purpura: A retrospective cohort study during the anti‐retroviral therapy era
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21692
Abstract: HIV‐associated thrombotic thrombocytopaenic purpura (TTP) is thought to represent the majority of current TTP diagnoses in South Africa (SA). read more here.
Keywords: associated thrombotic; thrombocytopaenic purpura; hiv associated; thrombotic thrombocytopaenic ... See more keywords
End Organ Damage Following Refractory/Recurrent Transplant Associated Thrombotic Microangiopathy (TA-TMA) in Pediatric Patients Undergoing Autologous Hematopoietic Cell Transplantation
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.431
Abstract: Background Transplant associated thrombotic microangiopathy (TA-TMA) is a known complication of autologous hematopoietic cell transplantation (aHCT), particularly in neuroblastoma. We describe our single institution experience of TA-TMA after aHCT in children. Methods Data were extracted… read more here.
Keywords: transplant associated; associated thrombotic; thrombotic microangiopathy; transplantation ... See more keywords
Linking Complement Activation, Coagulation, and Neutrophils in Transplant-Associated Thrombotic Microangiopathy.
Sign Up to like & getrecommendations! Published in 2019 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0039-1692721
Abstract: Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe and life-threatening complication of hematopoietic cell transplantation (HCT) that often coincides with graft-versus-host-disease (GVHD). Although endothelial damage seems to be the common denominator for both disorders, the role… read more here.
Keywords: coagulation; associated thrombotic; activation coagulation; transplant associated ... See more keywords
Snakebite-associated thrombotic microangiopathy: an Australian prospective cohort study [ASP30].
Sign Up to like & getrecommendations! Published in 2021 at "Clinical toxicology"
DOI: 10.1080/15563650.2021.1948559
Abstract: BACKGROUND Snakebite-associated thrombotic microangiopathy (TMA) occurs in a subset of patients with venom-induced consumption coagulopathy (VICC) following snakebite. Acute kidney injury (AKI) is the commonest end-organ manifestation of TMA. The epidemiology, diagnostic features, outcomes, and… read more here.
Keywords: prospective cohort; associated thrombotic; snakebite associated; tma ... See more keywords
Transplant-associated thrombotic microangiopathy: elucidating prevention strategies and identifying high-risk patients
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2021.1960816
Abstract: ABSTRACT Introduction Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (TA-TMA) is a severe complication of transplant. TA-TMA is a multifactorial disease where generalized endothelial dysfunction leads to microangiopathic hemolytic anemia, intravascular platelet activation, and formation of… read more here.
Keywords: risk; associated thrombotic; transplant; tma ... See more keywords
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of clinical pharmacology"
DOI: 10.1080/17512433.2023.2220963
Abstract: INTRODUCTION Snakebite is a neglected public health issue causing death and disability, disproportionately affecting tropical and subtropical resource poor countries globally. Snakebite-associated thrombotic microangiopathy (TMA) occurs in a subset of snakebites and is associated with… read more here.
Keywords: snakebite associated; associated thrombotic; associated tma; thrombotic microangiopathy ... See more keywords
Upregulation of HIF‐1α contributes to complement activation in transplantation‐associated thrombotic microangiopathy
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18377
Abstract: Transplantation‐associated thrombotic microangiopathy (TA‐TMA) is a severe complication of haematopoietic stem cell transplantation (HSCT). Complement activation is involved in the development of TA‐TMA. However, the underlying mechanism is unclear. Therefore, 21 samples of TA‐TMA and… read more here.
Keywords: transplantation associated; complement activation; associated thrombotic; hif ... See more keywords
What complements complement in transplant‐associated thrombotic microangiopathy?
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18402
Abstract: Transplant‐associated thrombotic microangiopathy remains a lethal complication of haematopoietic stem cell transplant and not all patients respond to terminal complement inhibitors. Qi et al. show that hypoxia‐inducible factor‐1α (HIF‐1α) may be a previously unrecognized driver… read more here.
Keywords: thrombotic microangiopathy; transplant; associated thrombotic; complements complement ... See more keywords
Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
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DOI: 10.1155/2021/5544188
Abstract: The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic… read more here.
Keywords: thrombotic diseases; associated thrombotic; risk factors; factors gastric ... See more keywords
Eculizumab in Transplant-Associated Thrombotic Microangiopathy
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DOI: 10.1177/1076029615599439
Abstract: Introduction: Transplant-associated thrombotic microangiopathy (TA-TMA) is a rare entity with no standard of care and high mortality, despite the use of plasma exchange. Methods: Using specific search terms, all cases having TA-TMA treated with eculizumab… read more here.
Keywords: associated thrombotic; transplant associated; transplant; eculizumab ... See more keywords