Polymorphisms in the canine IL7R 3′UTR are associated with thymic output in Labrador retriever dogs and influence post‐transcriptional regulation by microRNA 185
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.12.008
Abstract: &NA; Interleukin‐7 (IL‐7) and its receptor (IL‐7R) are essential for T cell development in the thymus, and changes in the IL‐7/IL‐7R pathway have been implicated in age‐associated thymic involution which results in a reduction of… read more here.
Keywords: thymic output; seed; output; il7r utr ... See more keywords
Neem leaf glycoprotein reverses tumor-induced and age-associated thymic involution to maintain peripheral CD8+ T cell pool.
Sign Up to like & getrecommendations! Published in 2020 at "Immunotherapy"
DOI: 10.2217/imt-2019-0168
Abstract: Aim: As tumor causes atrophy in the thymus to target effector-T cells, this study is aimed to decipher the efficacy of neem leaf glycoprotein (NLGP) in tumor- and age-associated thymic atrophy. Materials & methods: Different thymus parameters were studied… read more here.
Keywords: leaf glycoprotein; age associated; associated thymic; cell ... See more keywords