Leukemia‐associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.477
Abstract: MLLT3 (AF9) is a nuclear transcription factor crucial for hematopoietic stem cell and progenitor cell maintenance, but its role during embryonic hematopoiesis remains uncertain. Here, we examine the role of mllt3 in developmental hematopoiesis during… read more here.
Keywords: embryogenesis; leukemia associated; transcription; associated transcription ... See more keywords
Activity of non-canonical pluripotency-associated transcription factors in goat cumulus-oocyte complexes
Sign Up to like & getrecommendations! Published in 2018 at "Livestock Science"
DOI: 10.1016/j.livsci.2018.03.018
Abstract: Abstract Pluripotency-associated transcription factors (PATFs) are involved in several cellular processes, such as transcription initiation, cellular metabolism, and cell fate determination in preimplantation embryos. Despite growing understanding of PATFs in pluripotent human and mouse cells,… read more here.
Keywords: transcription; associated transcription; pluripotency associated; non canonical ... See more keywords
Knockdown of p66Shc Alters Lineage-Associated Transcription Factor Expression in Mouse Blastocysts
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells and Development"
DOI: 10.1089/scd.2018.0131
Abstract: The p66Shc adaptor protein regulates apoptosis and senescence during early mammalian development. However, p66Shc expression during mouse preimplantation development is upregulated at the blastocyst stage. Our objective was to determine the biological function of p66Shc… read more here.
Keywords: associated transcription; expression; p66shc; lineage associated ... See more keywords
Microphthalmia-associated transcription factors activate mTORC1 through RagD GTPase gene expression.
Sign Up to like & getrecommendations! Published in 2017 at "Translational cancer research"
DOI: 10.21037/tcr.2017.09.31
Abstract: The mechanistic target of rapamycin complex 1 (mTORC1) is a major serine/threonine kinase that stimulates cellular anabolic processes including protein and lipid synthesis while suppressing catabolic processes such as autophagy in response to growth factors… read more here.
Keywords: activate mtorc1; anabolic processes; factors activate; associated transcription ... See more keywords
Microphthalmia-Associated Transcription Factor: A Differentiation Marker in Uveal Melanoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108861
Abstract: Microphthalmia-associated transcription factor (MITF) is an important regulator of melanogenesis and melanocyte development. In cutaneous melanoma, MITF loss has been linked to an increased expression of stem cell markers, a shift in epithelial-to-mesenchymal transition (EMT)-related… read more here.
Keywords: mitf; melanoma; associated transcription; expression ... See more keywords