PARP1 associates with R-loops to promote their resolution and genome stability
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DOI: 10.1093/nar/gkad066
Abstract: Abstract PARP1 is a DNA-dependent ADP-Ribose transferase with ADP-ribosylation activity that is triggered by DNA breaks and non-B DNA structures to mediate their resolution. PARP1 was also recently identified as a component of the R-loop-associated… read more here.
Keywords: associates loops; promote resolution; parp1; loops promote ... See more keywords