Apolipoprotein-E (Apoe) ε4 and cognitive decline over the adult life course
Sign Up to like & getrecommendations! Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-017-0064-8
Abstract: We tested the association between APOE-ε4 and processing speed and memory between ages 43 and 69 in a population-based birth cohort. Analyses of processing speed (using a timed letter search task) and episodic memory (a… read more here.
Keywords: age; decline; association apoe; processing speed ... See more keywords
Association between APOE genotype and microglial cell morphology.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlad031
Abstract: APOE is the largest genetic risk factor for late-onset Alzheimer disease (AD) with E4 conferring an increased risk for AD compared to E3. The ApoE protein can impact diverse pathways in the brain including neuroinflammation… read more here.
Keywords: morphology; smtg; apoe isoforms; dementia ... See more keywords
Association of APOE polymorphisms with multibacillary leprosy
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Dermatology"
DOI: 10.1111/bjd.16361
Abstract: The authors justly conclude that each of the studied instruments assesses different aspects of the multidimensional impact that AD has on patients, with only partial overlap. This means that each instrument has a potential added… read more here.
Keywords: multibacillary leprosy; apoe polymorphisms; association apoe; polymorphisms multibacillary ... See more keywords
Neurostructural and neurocognitive correlates of APOE ε4 in youth bipolar disorder
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Psychopharmacology"
DOI: 10.1177/02698811221147151
Abstract: Background: Bipolar disorder (BD) is a clinical risk factor for Alzheimer’s disease (AD). Apolipoprotein E ε4 (APOE ε4), a genetic risk factor for AD, has been associated with brain structure and neurocognition in healthy youth.… read more here.
Keywords: neurostructural neurocognitive; disorder; neurocognitive correlates; bipolar disorder ... See more keywords
Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function
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DOI: 10.3233/jad-210673
Abstract: Background: The Apolipoprotein E (APOE) ɛ4 allele has been linked to increased tau phosphorylation and tangle formation. APOE ɛ4 carriers with elevated tau might be at the higher risk for Alzheimer’s disease (AD) progression. Previous… read more here.
Keywords: tau181 preclinical; disease; association apoe; hippocampus ... See more keywords
Association of ApoE gene polymorphisms with serum lipid levels and the risk of type 2 diabetes mellitus in the Chinese Han population of central China
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.15226
Abstract: Background Apolipoprotein E (ApoE) is involved in lipid transformation and metabolism. Although some studies have examined the association between ApoE polymorphisms and the risk of type 2 diabetes mellitus (T2DM), the findings differ depending on… read more here.
Keywords: central china; chinese han; han population; population ... See more keywords