The association between HSD3B1 genotype and steroid metabolism in normal and prostate cancer (PCa) tissue.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.tps155
Abstract: TPS155Background: The common germline variant HSD3B1(1245C) encodes for a gain-of-function in 3βHSD1 which is associated with a shorter duration of response to androgen deprivation therapy (ADT) and more rapid disease progression to castration resistant PCa… read more here.
Keywords: genotype; tissue; hsd3b1; association hsd3b1 ... See more keywords