Association of phosphatidylinositol 3-kinase (PI3K) pathway activation with increased immune checkpoint expression in colorectal cancer (CRC) patients.
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DOI: 10.1200/jco.2018.36.4_suppl.653
Abstract: 653Background: PI3K pathway is a known modulator of anti-tumor immune response and is frequently activated in CRC through genetic alterations such as PTEN loss (PTENloss) and PIK3CA mutations (PIK3... read more here.
Keywords: pathway activation; kinase pi3k; association phosphatidylinositol; activation increased ... See more keywords