Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population
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DOI: 10.1007/s00439-020-02222-7
Abstract: While the Arabian population has a high prevalence of metabolic disorders, it has not been included in global studies that identify genetic risk loci for metabolic traits. Determining the transferability of such largely Euro-centric established… read more here.
Keywords: association signals; genome wide; risk; metabolic traits ... See more keywords
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences
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DOI: 10.1371/journal.pgen.1009019
Abstract: Loci identified in genome-wide association studies (GWAS) can include multiple distinct association signals. We sought to identify the molecular basis of multiple association signals for adiponectin, a hormone involved in glucose regulation secreted almost exclusively… read more here.
Keywords: loci; allelic heterogeneity; association; association signals ... See more keywords