Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling
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DOI: 10.7554/elife.78810
Abstract: The transcription factor TEAD, together with its coactivator YAP/TAZ, is a key transcriptional modulator of the Hippo pathway. Activation of TEAD transcription by YAP has been implicated in a number of malignancies, and this complex… read more here.
Keywords: association suppresses; yap tead; yap; tead association ... See more keywords