Rare‐variant association tests in longitudinal studies, with an application to the Multi‐Ethnic Study of Atherosclerosis (MESA)
Sign Up to like & getrecommendations! Published in 2017 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22081
Abstract: Over the past few years, an increasing number of studies have identified rare variants that contribute to trait heritability. Due to the extreme rarity of some individual variants, gene‐based association tests have been proposed to… read more here.
Keywords: longitudinal studies; study; association; association tests ... See more keywords
A simple and accurate method to determine genomewide significance for association tests in sequencing studies
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DOI: 10.1002/gepi.22183
Abstract: Whole‐exome sequencing (WES) and whole‐genome sequencing (WGS) studies are underway to investigate the impact of genetic variants on complex diseases and traits. It is customary to perform single‐variant association tests for common variants and region‐based… read more here.
Keywords: simple accurate; association tests; genomewide significance; significance ... See more keywords
Title: Brief Implicit Association Tests of Stigmatizing Attitudes, Awareness of Mental Distress and Label-Avoidance: A Study in People with Depressive Symptoms
Sign Up to like & getrecommendations! Published in 2019 at "Community Mental Health Journal"
DOI: 10.1007/s10597-019-00372-1
Abstract: This study aims to develop and implement brief implicit association tests (BIATs) assessing stigmatizing attitudes towards mental illness, awareness of mental distress and self-identification as having a mental illness. We recruited 229 people (age range… read more here.
Keywords: stigmatizing attitudes; implicit association; awareness mental; association tests ... See more keywords
OPATs: Omnibus P-value association tests
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DOI: 10.1093/bib/bbx068
Abstract: Abstract Combining statistical significances (P‐values) from a set of single‐locus association tests in genome‐wide association studies is a proof‐of‐principle method for identifying disease‐associated genomic segments, functional genes and biological pathways. We review P‐value combinations for… read more here.
Keywords: based association; association; association tests; value combinations ... See more keywords
Comparing mixed models and Random Forest association tests using naturalgwas and a Striped Bass SNP data set
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DOI: 10.1111/1755-0998.13701
Abstract: In this study, we used the phenotype simulation package naturalgwas to test the performance of Zhao's Random Forest method in comparison to an uncorrected Random Forest test, latent factor mixed models (LFMM), genome‐wide efficient mixed… read more here.
Keywords: striped bass; random forest; association tests; mixed models ... See more keywords