Experimental and computational evidence of halogen bonds involving astatine
Sign Up to like & getrecommendations! Published in 2018 at "Nature Chemistry"
DOI: 10.1038/s41557-018-0011-1
Abstract: The importance of halogen bonds—highly directional interactions between an electron-deficient σ-hole moiety in a halogenated compound and an acceptor such as a Lewis base—is being increasingly recognized in a wide variety of fields from biomedicinal… read more here.
Keywords: astatine; chemistry; involving astatine; experimental computational ... See more keywords
Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211
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DOI: 10.3390/ph16040595
Abstract: To enhance targeting efficacy in the radioimmunotherapy of disseminated cancer, several pretargeting strategies have been developed. In pretargeted radioimmunotherapy, the tumor is pretargeted with a modified monoclonal antibody that has an affinity for both tumor… read more here.
Keywords: astatine; chemistry; disseminated cancer; alpha therapy ... See more keywords