Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.34714
Abstract: Key Points Question Can a symptom-based screening tool (CHILDhood Asthma Risk Tool [CHART]) improve the ability to identify children at risk of persistent asthma symptoms and health care use? Findings In this diagnostic study of… read more here.
Keywords: high risk; tool; asthma; symptom based ... See more keywords
Genomic evidence for dysregulated glutamine metabolism in the asthmatic airway epithelium
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12178
Abstract: To the Editor, Airway epithelial cells (AECs) play a critical role in lung tissue homeostasis and disease. In asthma, AECs can promote the development of airway inflammation and remodeling through the secretion and regulation of… read more here.
Keywords: metabolism; glutamine metabolism; asthma; differentially expressed ... See more keywords
Symptom control and health‐related quality of life in allergic rhinitis with and without comorbid asthma: A multicentre European study
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12209
Abstract: Abstract Background Allergic rhinitis (AR) is a major non‐communicable disease that affects the health‐related quality of life (HRQoL) of patients. However, data on HRQoL and symptom control in AR patients with comorbid asthma (AR +… read more here.
Keywords: symptom control; control; asthma; comorbid asthma ... See more keywords
Association of asthma genetic variants with asthma‐associated traits reveals molecular pathways of eosinophilic asthma
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12239
Abstract: Abstract Introduction Asthma is a complex, polygenic, heterogenous inflammatory disease. Recently, we generated a list of 128 independent single nucleotide polymorphisms (SNPs) associated with asthma in genome‐wide association studies. However, it is unknown if asthma… read more here.
Keywords: snps associated; asthma; snps; asthma associated ... See more keywords
Lung epithelial cells: upstream targets in type 2-high asthma.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250106
Abstract: Over the last years, technological advances in the field of asthma have led to the identification of two disease endotypes, namely type 2-high and type 2-low asthma, characterized by different pathophysiologic mechanisms at a cellular… read more here.
Keywords: asthma; lung epithelial; epithelial cells; type high ... See more keywords
Pulmonary MRI and Cluster Analysis Help Identify Novel Asthma Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28152
Abstract: Outside eosinophilia, current clinical asthma phenotypes do not show strong relationships with disease pathogenesis or treatment responses. While chest x‐ray computed tomography (CT) phenotypes have previously been explored, functional MRI measurements provide complementary phenotypic information. read more here.
Keywords: mri cluster; cluster analysis; asthma; analysis help ... See more keywords
Misdiagnosis of asthma in schoolchildren
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23541
Abstract: Background: A correct diagnosis of asthma is the cornerstone of asthma management. Few pediatric studies have examined the accuracy of physician‐diagnosed asthma. Objectives: We determined the accuracy of parent reported physician‐diagnosed asthma in children sampled… read more here.
Keywords: diagnosis; diagnosis asthma; physician diagnosed; study ... See more keywords
Multidisciplinary treatment in children with problematic severe asthma: A prospective evaluation
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23623
Abstract: Objective: For children with problematic severe asthma, achieving adequate control of asthma is difficult. The aim of this prospective observational study was to evaluate the effects of intensive multidisciplinary inpatient treatment on multiple outcome variables… read more here.
Keywords: outcome; treatment; children problematic; severe asthma ... See more keywords
The association between secondhand smoke and childhood asthma: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24961
Abstract: Secondhand smoke (SHS) exposure can trigger asthma exacerbations in children. Different studies have linked increased asthma symptoms and even deaths in children with SHS, but the risk has not been quantified uniformly across studies. We… read more here.
Keywords: childhood asthma; smoke childhood; secondhand smoke; asthma ... See more keywords
Asthma and COVID‐19: An early inpatient and outpatient experience at a US children's hospital
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25514
Abstract: Initially, persistent asthma was deemed a risk factor for severe COVID‐19 disease. However, data suggests that asthmatics do not have an increased risk of COVID‐19 infection or disease. There is a paucity of data describing… read more here.
Keywords: covid early; inpatient outpatient; asthma covid; outpatient experience ... See more keywords
Pediatric asthma control during the COVID-19 pandemic: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric pulmonology"
DOI: 10.1002/ppul.25736
Abstract: BACKGROUND With the onset of the COVID-19 pandemic, many experts expected that asthma-associated morbidity because of SARS-CoV-2 infection would dramatically increase. However, some studies suggested that there was no apparent increasing in asthma related morbidity… read more here.
Keywords: pediatric asthma; control covid; asthma; asthma control ... See more keywords