Respiratory Syncytial Virus Exacerbates OVA-mediated asthma in mice through C5a-C5aR regulating CD4+T cells Immune Responses
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15471-w
Abstract: Asthma exacerbation could be induced by respiratory syncytial virus (RSV), and the underlying pathogenic mechanism is related to complement activation. Although complement might regulate CD4+T cells immune responses in asthma model, this regulation existed in… read more here.
Keywords: cells immune; cd4 cells; immune responses; asthma mice ... See more keywords
Metabolic profiling of asthma in mice and the interventional effects of SPA using liquid chromatography and Q-TOF mass spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00025a
Abstract: Asthma is a chronic inflammatory lung disease that leads to 250 000 deaths annually. There is a need to better understand asthma by identifying new pathogenic molecules. We conducted a liquid-chromatography time-of-flight mass spectrometry (LC-Q-TOF-MS)-based metabolomics… read more here.
Keywords: asthma mice; liquid chromatography; mass spectrometry;
Inhibitions of HMGB1 and TLR4 alleviate DINP-induced asthma in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology research"
DOI: 10.1039/c9tx00048h
Abstract: We studied the effects of high mobility group box chromosomal protein 1 (HMGB1) and toll-like receptor (TLR4) in diisonoyl phthalate (DINP)-induced asthma. Mice with DINP-induced asthma were treated with a TLR4-signaling inhibitor or anti-HMGB1 antibody,… read more here.
Keywords: induced asthma; dinp induced; hmgb1; asthma mice ... See more keywords
Human amniotic membrane mesenchymal stem cell‐conditioned medium reduces inflammatory factors and fibrosis in ovalbumin‐induced asthma in mice
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep088911
Abstract: What is the central question of this study? Is mesenchymal stem cell‐conditioned medium capable of improving the pathological alterations of ovalbumin‐induced asthma in mice? What is the main finding and its importance? Our study indicated… read more here.
Keywords: stem cell; conditioned medium; cell conditioned; asthma mice ... See more keywords
Zeaxanthin attenuates OVA-induced allergic asthma in mice by regulating the p38 MAPK/β-catenin signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i5.664
Abstract: BACKGROUND Asthma is a heterogeneous and complex chronic airway disease with a high incidence rate, characterized by chronic airway inflammation. Although the anti-inflammatory effect of zeaxanthin has been demonstrated in various disease models, its explicit… read more here.
Keywords: asthma mice; zeaxanthin; ova induced; allergic asthma ... See more keywords
Chryseriol attenuates the progression of OVA-induced asthma in mice through NF-κB/HIF-1α and MAPK/STAT1 pathways.
Sign Up to like & getrecommendations! Published in 2023 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v51i1.776
Abstract: BACKGROUND Asthma is a hackneyed chronic inflammatory disease of the airway. Chryseriol (CSR) is a kind of flavonoid, and has the effect of bronchiectasis, indicating its potential application for treating respiratory diseases. However, the functions… read more here.
Keywords: stat1 pathways; treatment; asthma mice; csr treatment ... See more keywords
Lipoxin A4 regulates PM2.5-induced severe allergic asthma in mice via the Th1/Th2 balance of group 2 innate lymphoid cells.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.03.02
Abstract: Background Urban particulate matter (PM) contributes to the increasing number of people with asthma, which is closely related to the development of industrialization. Especially, PM with an aerodynamic diameter of read more here.
Keywords: group innate; innate lymphoid; asthma mice; lymphoid cells ... See more keywords