Butylphthalide ameliorates airway inflammation and mucus hypersecretion via NF-κB in a murine asthma model.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105873
Abstract: Butylphthalide (NBP) is a phthalide compound contained in Angelicae Sinensis Radix which is one of the most widely used traditional Chinese medicines. This study aims to explore the therapeutic effect of NBP on airway inflammation,… read more here.
Keywords: mucus hypersecretion; airway inflammation; mucus; asthma model ... See more keywords
MiRNA-451a inhibits airway remodeling by targeting Cadherin 11 in an allergic asthma model of neonatal mice.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106440
Abstract: Airway remodeling happens in childhood asthma, in parallel with, but not necessarily subsequent to, airway inflammation. The differentiation of airway epithelial cells into myofibroblasts via epithelial-mesenchymal-transition (EMT) is one of the mechanisms underlying airway remodeling.… read more here.
Keywords: cdh11; mirna 451a; asthma model; airway remodeling ... See more keywords
Anti‐inflammatory effect a specific Lactiplantibacillus plantarum in an ovalbumin‐induced asthma model
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.13014
Abstract: Autoimmune, allergic, and respiratory inflammatory diseases are some of the most important health issues worldwide. Disorders of the gut microbiota have been associated with the induction of allergic and inflammatory diseases, and probiotics are being… read more here.
Keywords: effect; asthma model; induced asthma; specific lactiplantibacillus ... See more keywords
Ferrostatin-1 and 3-Methyladenine Ameliorate Ferroptosis in OVA-Induced Asthma Model and in IL-13-Challenged BEAS-2B Cells
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9657933
Abstract: Ferroptosis was reported to be involved in the occurrence and development of asthma. However, the potential mechanism underlying the role of ferroptosis in asthma remains unclear. In this study, we established the mouse asthma model… read more here.
Keywords: ferroptosis; asthma model; ferrostatin methyladenine; beas cells ... See more keywords
A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2020-0452oc
Abstract: Orai1 is a plasma membrane Ca2+ channel that mediates store operated Ca2+ entry (SOCE) and regulates inflammation. Short palate lung and nasal epithelial clone 1 (SPLUNC1) is an asthma gene modifier which inhibits Orai1/SOCE via… read more here.
Keywords: asthma model; inhibits orai1; microscopy; inflammation murine ... See more keywords
IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model
Sign Up to like & getrecommendations! Published in 2019 at "European Respiratory Journal"
DOI: 10.1183/13993003.01510-2018
Abstract: Steroid insensitivity constitutes a major problem for asthma management. Toluene diisocyanate (TDI) is one of the leading allergens of asthma that induces both T-helper Th2 and Th17 responses, and is often associated with poor responsiveness… read more here.
Keywords: induced asthma; airway inflammation; asthma model; model ... See more keywords
Intravenous Mesenchymal Stem Cell Administration Modulates Monocytes/Macrophages and Ameliorates Asthmatic Airway Inflammation in a Murine Asthma Model
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.0038
Abstract: Although asthma is a common chronic airway disease that responds well to anti-inflammatory agents, some patients with asthma are unresponsive to conventional treatment. Mesenchymal stem cells (MSCs) have therapeutic potential for the treatment of inflammatory… read more here.
Keywords: murine asthma; asthma model; mscs; huc mscs ... See more keywords