Obese asthma phenotypes display distinct plasma biomarker profiles
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12238
Abstract: Abstract Background Obese asthma is a complex phenotype and further characterization of the pathophysiology is needed. This study aimed to explore inflammation‐related plasma biomarkers in lean and overweight/obese asthmatics. Methods We elucidated levels of inflammation‐related… read more here.
Keywords: overweight obese; factor; asthma phenotypes; distinct plasma ... See more keywords
Pulmonary MRI and Cluster Analysis Help Identify Novel Asthma Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28152
Abstract: Outside eosinophilia, current clinical asthma phenotypes do not show strong relationships with disease pathogenesis or treatment responses. While chest x‐ray computed tomography (CT) phenotypes have previously been explored, functional MRI measurements provide complementary phenotypic information. read more here.
Keywords: mri cluster; cluster analysis; asthma; analysis help ... See more keywords
Role of airway epithelial cells in the development of different asthma phenotypes.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2019.109523
Abstract: The term (bronchial) asthma describes a disorder syndrome that comprises several disease phenotypes, all characterized by chronic inflammation in the bronchial epithelium, with a variety of subsequent functional consequences. Thus, the epithelium in the conducting… read more here.
Keywords: epithelial cells; different asthma; asthma phenotypes; development different ... See more keywords
Toward a better understanding of severe asthma phenotypes in Latin America: results from the PREPARE study
Sign Up to like & getrecommendations! Published in 2023 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2023.2174328
Abstract: Abstract Objective Data on severe asthma phenotypes in Latin America are lacking. The PREPARE study describes the prevalence of certain determinants of severe asthma among patients in 5 Latin American countries with blood eosinophil counts… read more here.
Keywords: prepare study; latin america; phenotypes latin; asthma phenotypes ... See more keywords
Asthma phenotypes in children and stratified pharmacological treatment regimens
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2017.1271322
Abstract: ABSTRACT Introduction: Asthma is the most common inflammatory disease in childhood. The interaction of genetic, environmental and host factors may contribute to the development of childhood asthma and defines its progress, including persistence and severity.… read more here.
Keywords: childhood asthma; asthma phenotypes; treatment; phenotypes children ... See more keywords
Allergic and Nonallergic Asthma Have Distinct Phenotypic and Genotypic Features
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000458151
Abstract: Background: Identification of asthma phenotypes enables a better understanding and management of this heterogeneous disease. Studies have reported associations between human leukocyte antigens (HLA) and asthma in different populations, but the results have been inconclusive… read more here.
Keywords: asthma phenotypes; asthma distinct; hla; nonallergic asthma ... See more keywords
ROLE OF INTERFERON-Γ AND INTERLUKIN-10 ON THE PATHOGENESIS OF ASTHMA PHENOTYPES IN SAUDI PATIENTS.
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Approximate Reasoning"
DOI: 10.21474/ijar01/5353
Abstract: * Al-Shehri AS 1, 2 , Al-Shehri SS 3 , Al-Hamidi AH 2 , Dalati TA 4 , Alhazmi AS 3 and Eid GE 2 . 1. Ministry of Health, Administration of Laboratory and Blood… read more here.
Keywords: interlukin pathogenesis; role interferon; asthma phenotypes; pathogenesis asthma ... See more keywords
Asthma phenotypes and endotypes in childhood.
Sign Up to like & getrecommendations! Published in 2021 at "Minerva medica"
DOI: 10.23736/s0026-4806.21.07332-8
Abstract: Asthma is a very heterogeneous disease and since early childhood many classifications have been proposed according to phenotype and endotype. The phenotype includes the clinical features of asthma such as age of onset, triggers, comorbidities,… read more here.
Keywords: endotypes childhood; phenotype; asthma phenotypes; phenotypes endotypes ... See more keywords
Eosinophilic Asthma, Phenotypes-Endotypes and Current Biomarkers of Choice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12071093
Abstract: Asthma phenotyping and endotyping are constantly evolving. Currently, several biologic agents have been developed towards a personalized approach to asthma management. This review will focus on different eosinophilic phenotypes and Th2-associated endotypes with eosinophilic inflammation.… read more here.
Keywords: eosinophilic asthma; asthma; current biomarkers; phenotypes endotypes ... See more keywords
Asthma: From Phenotypes to Personalized Medicine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12111853
Abstract: Asthma is a heterogeneous disease of the airways with a high prevalence worldwide characterized by chronic inflammation [...]. read more here.
Keywords: medicine asthma; personalized medicine; asthma phenotypes; medicine ... See more keywords
Metabolic Phenotypes in Asthmatic Adults: Relationship with Inflammatory and Clinical Phenotypes and Prognostic Implications
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11080534
Abstract: Bronchial asthma is a chronic disease that affects individuals of all ages. It has a high prevalence and is associated with high morbidity and considerable levels of mortality. However, asthma is not a single disease,… read more here.
Keywords: asthma phenotypes; phenotypes asthmatic; asthmatic adults; metabolic phenotypes ... See more keywords