Effects of anti‐IL5 biological treatments on blood IgE levels in severe asthmatic patients: A real‐life multicentre study (BIONIGE)
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DOI: 10.1002/clt2.12143
Abstract: Abstract Background Mepolizumab and benralizumab are clinically effective biological treatments for severe eosinophilic asthmatic patients by hampering eosinophilic inflammation. The effects of these compound on the immunoglobulin (Ig)E T2 component are virtually unknown. Objectives To… read more here.
Keywords: asthmatic patients; ige levels; blood; biological treatments ... See more keywords
How reliably can algorithms identify eosinophilic asthma phenotypes using non‐invasive biomarkers?
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DOI: 10.1002/clt2.12182
Abstract: Abstract Background and Aims Asthma is a heterogeneous respiratory disease that encompasses different inflammatory and functional endophenotypes. Many non‐invasive biomarkers has been investigated to its pathobiology. Heany et al proposed a clinical algorithm that classifies… read more here.
Keywords: asthmatic patients; non invasive; reliably algorithms; invasive biomarkers ... See more keywords
Laryngeal dysfunction is prominent in asthmatic women treated by inhaled corticosteroids
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DOI: 10.1002/clt2.12211
Abstract: Abstract Background Dysphonia is a frequent comorbidity of asthma and has been suggested to be a local side effect of inhaled corticosteroids due to laryngeal candidiasis. We hypothesized that dysphonia in asthmatics was not due… read more here.
Keywords: asthmatic patients; laryngeal dysfunction; treated inhaled; inhaled corticosteroids ... See more keywords
Oxidative stress in patients with asthma and its relation to uncontrolled asthma.
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DOI: 10.1002/jcla.24345
Abstract: This study aims to evaluate markers of oxidative stress in Tunisian asthmatic patients and investigate whether their markers are correlated with uncontrolled asthma. This prospective cohort study was conducted on 48 healthy subjects and 60 patients… read more here.
Keywords: asthmatic patients; patients asthma; oxidative stress; activity ... See more keywords
Safety of biologics in severe asthmatic patients with SARS‐CoV‐2 infection: A prospective study
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26298
Abstract: Asthma guidelines have recommended continuing treatment with biologics during coronavirus disease 2019 (COVID‐19) pandemic. However, a continuation of treatment with biologics in patients with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been little investigated. read more here.
Keywords: asthmatic patients; safety biologics; severe asthmatic; patients sars ... See more keywords
Possible therapeutic effect of carvacrol on asthmatic patients: A randomized, double blind, placebo‐controlled, Phase II clinical trial
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.5967
Abstract: The relaxant effects of carvacrol, a phenolic monoterpene, on tracheal smooth muscle and its preventive effect on asthmatic animals were reported. The effect of carvacrol in asthmatic patients was examined in the placebo group (Group… read more here.
Keywords: treatment; group; effect; effect carvacrol ... See more keywords
Comparative study of oxidative status in blood of asthmatic patients
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DOI: 10.1007/s00580-018-2701-x
Abstract: Bronchial asthma (BA) is a chronic inflammatory lungs disease, resulting in an airflow restriction, hyperactivity, and airway remodeling. The aim of present study is to investigate and compare the oxidative stress levels in blood of… read more here.
Keywords: blood asthmatic; study; asthmatic patients; oxidative stress ... See more keywords
A review on the effect of COVID-19 in type 2 asthma and its management
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DOI: 10.1016/j.intimp.2020.107309
Abstract: Background COVID-19 is considered the most critical health pandemic of 21st century. Due to extremely high transmission rate, people are more susceptible to viral infection. COVID-19 patients having chronic type-2 asthma prevails a major risk… read more here.
Keywords: type asthma; covid; review; covid type ... See more keywords
Comparative efficacy and tolerability of beclomethasone/formoterol and fluticasone/salmeterol fixed combination in Taiwanese asthmatic patients.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.12.005
Abstract: BACKGROUND The study was designed to compare the efficacy and tolerability of a fixed combination of extra-fine beclomethasone and formoterol, with the fixed combination fluticasone and salmeterol in Taiwanese asthmatic patients. METHODS This was a… read more here.
Keywords: combination; taiwanese asthmatic; efficacy tolerability; fixed combination ... See more keywords
The effects of the antecedent use of inhaled steroid on the clinical course of COVID-19: A retrospective study of asthmatic patients
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DOI: 10.1016/j.jiph.2021.12.003
Abstract: Background There is conflicting evidence regarding the effect of asthma and its different therapeutic options on COVID-19 severity and the clinical outcomes. Aim This study aimed to investigate the relationship between using inhaled corticosteroids (ICS)… read more here.
Keywords: asthmatic patients; study; covid severity; ics non ... See more keywords
Reduced sarcoplasmic reticulum Ca2+ ATPase activity underlies skeletal muscle wasting in asthma.
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DOI: 10.1016/j.lfs.2021.119296
Abstract: AIMS Skeletal muscle mass and strength are reduced in asthma and contribute to compromised functional capacity in asthmatic patients. However, an effective pharmacological intervention remains elusive, partly because molecular mechanisms dictating muscle decline in asthma… read more here.
Keywords: skeletal muscle; muscle; reticulum ca2; sarcoplasmic reticulum ... See more keywords