Articles with "astragalin" as a keyword



Apoptotic Effect of Astragalin in Melanoma Skin Cancers via Activation of Caspases and Inhibition of Sry‐related HMg‐Box Gene 10

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Published in 2017 at "Phytotherapy Research"

DOI: 10.1002/ptr.5895

Abstract: Though Astragalin (kaempferol‐3‐glucoside) contained in Paeonia lactiflora and other plants was known to have anti‐oxidant, antiinflammatory, and anti‐tumor activity, the anti‐tumor mechanism of Astragalin has never been reported in melanomas until now. Thus, in the… read more here.

Keywords: melanoma; sry related; a375p mel; astragalin ... See more keywords

Astragalin reduces lipopolysaccharide-induced acute lung injury in rats via induction of heme oxygenase-1.

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Published in 2019 at "Archives of pharmacal research"

DOI: 10.1007/s12272-019-01171-8

Abstract: Astragalin, a bioactive component of medicinal plants such as Rosa agrestis, has anti-inflammatory and antioxidant features. Induction of heme oxygenase (HO)-1 is an effective strategy to reduce excessive generated oxidants during the pathogenesis of acute… read more here.

Keywords: astragalin; heme oxygenase; induction heme; lung injury ... See more keywords

Analysis of the therapeutic potential of astragalin: insights into target interactions and mechanisms

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Published in 2025 at "Xenobiotica"

DOI: 10.1080/00498254.2025.2559962

Abstract: Abstract Astragalin (AST), a flavonoid, shows promise for neurodegenerative diseases like Parkinson’s disease (PD), cognitive impairment (CI), and depression. However, its efficacy in treating neurodegenerative diseases and the underlying molecular mechanisms remain unclear. This study… read more here.

Keywords: ast metabolites; therapeutic potential; astragalin; analysis therapeutic ... See more keywords

Astragalin attenuates caerulein-induced acute pancreatitis by targeting the NLRP3 signaling pathway and gut microbiota

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Published in 2025 at "Bioresources and Bioprocessing"

DOI: 10.1186/s40643-025-00977-3

Abstract: Acute pancreatitis (AP) has caused great concern worldwide due to its serious threat to human health. Astragalin is a bioactive natural flavonoid compound with several pharmacological activities, but it remains unclear about its effect on… read more here.

Keywords: gut microbiota; pharmacology; astragalin; nlrp3 signaling ... See more keywords