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   Articles with "astragalus polysaccharides" as a keyword



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pH-responsive Astragalus polysaccharides-loaded poly(lactic-co-glycolic acid) nanoparticles and their in vitro immunogenicity.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2018.12.156

Abstract: Astragalus polysaccharides (APS) have long been well known as immune boosters, but have not been fully exploited in clinical settings. Here, poly(lactic-co-glycolic acid) (PLGA) was used to form a nanocarrier for APS to enhance its… read more here.

Keywords: poly lactic; astragalus polysaccharides; responsive apsps; lactic glycolic ... See more keywords
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Astragalus polysaccharides inhibits cardiomyocyte apoptosis during diabetic cardiomyopathy via the endoplasmic reticulum stress pathway.

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recommendations! Published in 2019 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2019.111857

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Traditional Chinese medicine Astragalus membranaceus (Fisch.) Bunge (AM) has been utilized for the treatment of diabetes mellitus and its complications for centuries. Astragalus polysaccharides (APS), the main bioactive ingredient extracted from the root… read more here.

Keywords: stress pathway; astragalus polysaccharides; apoptosis; diabetic cardiomyopathy ... See more keywords
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The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides

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recommendations! Published in 2019 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2019.03.019

Abstract: Multiple sclerosis (MS) is an inflammatory demyelinating disease of CNS. Astragalus polysaccharides (APS), the main active extract from astragalus membranaceus which is a kind of traditional Chinese medicinal herb, is associated with a variety of… read more here.

Keywords: regulated suppression; astragalus polysaccharides; autoimmune encephalomyelitis; pathway regulated ... See more keywords
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Immune-enhancing effects of Astragalus polysaccharides and Ganoderma lucidum polysaccharides on Vibrio harveyi flgJ DNA vaccine in grouper.

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recommendations! Published in 2022 at "Journal of fish diseases"

DOI: 10.1111/jfd.13728

Abstract: Astragalus polysaccharides (APS) and Ganoderma lucidum polysaccharides (GLP) have been shown to possess strong immunoregulatory properties in aquatic animals. In this study, the fragment containing Vibrio harveyi flgJ gene was ligated into pcDNA3.1(+) vector and… read more here.

Keywords: aps glp; grouper; dna vaccine; astragalus polysaccharides ... See more keywords

Effect of Astragalus Polysaccharides on Cardiac Dysfunction in db/db Mice with Respect to Oxidant Stress

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recommendations! Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/8359013

Abstract: Objective Oxidant stress plays an important role in the development of diabetic cardiomyopathy. Previously we reported that Astragalus polysaccharides (APS) rescued heart dysfunction and cardinal pathological abnormalities in diabetic mice. In the current study, we… read more here.

Keywords: target genes; astragalus polysaccharides; dysfunction; oxidant stress ... See more keywords

Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics

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recommendations! Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.00230

Abstract: Chitosan (CTS) constitutes a promising area in treatment of nose-related diseases as a nasal drug delivery carrier. Astragalus polysaccharide (APS) significantly attenuates eosinophils and neutrophil-dominant airway inflammation, and it has a potential pharmaceutical application in… read more here.

Keywords: cts microspheres; aps cts; astragalus polysaccharides; polysaccharides chitosan ... See more keywords

Pharmacological Effects and Molecular Protective Mechanisms of Astragalus Polysaccharides on Nonalcoholic Fatty Liver Disease

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.854674

Abstract: Nonalcoholic fatty liver disease (NAFLD) has been renamed metabolic dysfunction-associated fatty liver disease (MAFLD), a condition for which there is now no authorized treatment. The search for new medications to treat MAFLD made from natural… read more here.

Keywords: nonalcoholic fatty; fatty liver; astragalus polysaccharides; liver disease ... See more keywords

Karnofsky Performance Status as A Predictive Factor for Cancer-Related Fatigue Treatment with Astragalus Polysaccharides (PG2) Injection—A Double Blind, Multi-Center, Randomized Phase IV Study

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recommendations! Published in 2019 at "Cancers"

DOI: 10.3390/cancers11020128

Abstract: Fatigue is a common and debilitating symptom in patients with advanced cancer, resulting in poor quality of life and reduced treatment efficacy. Phytotherapeutic agents have shown potential effects to relieve cancer-related fatigue in these patients.… read more here.

Keywords: astragalus polysaccharides; treatment; cancer related; related fatigue ... See more keywords