OpenSpec Enables Detecting Unexpected Modifications from Proteomics Data Generated by Orbitrap Astral Mass Spectrometer.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c03055
Abstract: The Orbitrap Astral mass spectrometer features outstanding speed, resolution, and sensitivity, making data-independent acquisition (DIA) the preferred method for deep profiling in shotgun proteomics. However, as for data generated by an Orbitrap Astral mass spectrometer,… read more here.
Keywords: chemistry; orbitrap astral; unexpected modifications; astral mass ... See more keywords
Expanding the landscape of aging via orbitrap astral mass spectrometry and tandem mass tag integration
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-60022-x
Abstract: Aging results in a progressive decline in physiological function due to the deterioration of essential biological processes. While proteomics offers insights into aging mechanisms, prior studies are limited in proteome coverage and lifespan range. To… read more here.
Keywords: age; tandem mass; orbitrap astral; mass tag ... See more keywords