Dilation of cortical capillaries is not related to astrocyte calcium signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24119
Abstract: The brain requires an adequate supply of oxygen and nutrients to maintain proper function as neuronal activity varies. This is achieved, in part, through neurovascular coupling mechanisms that mediate local increases in blood flow through… read more here.
Keywords: astrocyte ca2; dilation; ca2 signaling; whisker stimulation ... See more keywords
Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1101/2020.12.16.422785
Abstract: Brain requires increased local cerebral blood flow (CBF) for as long as necessary during neuronal activation to match O2 and glucose supply with demand – termed functional hyperemia. Ca2+ elevation in astrocytes can drive arteriole… read more here.
Keywords: functional hyperemia; hyperemia; arteriole dilation; astrocyte ca2 ... See more keywords