Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M.
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DOI: 10.1016/j.immuni.2021.01.004
Abstract: Pathologic roles of innate immunity in neurologic disorders are well described, but their beneficial aspects are less understood. Dectin-1, a C-type lectin receptor (CLR), is largely known to induce inflammation. Here, we report that Dectin-1… read more here.
Keywords: autoimmune neuroinflammation; myeloid cell; card9 independent; cell astrocyte ... See more keywords