Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia
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DOI: 10.1186/s40478-019-0735-1
Abstract: Astrogliosis and activation of microglia are hallmarks of prion diseases in humans and animals. Both were viewed to be rather independent events in disease pathophysiology, with proinflammatory microglia considered to be the potential neurotoxic species… read more here.
Keywords: astrocytes highly; highly abundant; prion; abundant prion ... See more keywords