Subcellular reorganization and altered phosphorylation of the astrocytic gap junction protein connexin43 in human and experimental temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23196
Abstract: Dysfunctional astrocytes are increasingly recognized as key players in the development and progression of mesial temporal lobe epilepsy (MTLE). One of the dramatic changes astrocytes undergo in MTLE with hippocampal sclerosis (HS) is loss of… read more here.
Keywords: gap; gap junction; astrocytic gap; phosphorylation ... See more keywords
Macro scale modelling of cortical spreading depression and the role of astrocytic gap junctions.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.09.006
Abstract: Neuronal activity evokes a localised increase in cerebral blood flow in a response known as neurovascular coupling (NVC), achieved through communication between a group of cells known as a neurovascular unit (NVU). Dysfunctional NVC can… read more here.
Keywords: gap; gap junctions; spreading depression; model ... See more keywords
Improved Perceptual Learning by Control of Extracellular GABA Concentration by Astrocytic Gap Junctions
Sign Up to like & getrecommendations! Published in 2018 at "Neural Computation"
DOI: 10.1162/neco_a_01027
Abstract: Learning of sensory cues is believed to rely on synchronous pre- and postsynaptic neuronal firing. Evidence is mounting that such synchronicity is not merely caused by properties of the underlying neuronal network but could also… read more here.
Keywords: gap; gap junctions; extracellular gaba; astrocytic gap ... See more keywords