Deletion of RE1‐silencing transcription factor in striatal astrocytes exacerbates manganese‐induced neurotoxicity in mice
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DOI: 10.1002/glia.24226
Abstract: Chronic manganese (Mn) overexposure causes a neurological disorder, referred to as manganism, exhibiting symptoms similar to parkinsonism. Dysfunction of the repressor element‐1 silencing transcription factor (REST) is associated with various neurodegenerative diseases such as Parkinson's… read more here.
Keywords: induced neurotoxicity; astrocytic rest; deletion; rest ... See more keywords