LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "astrocytoma" as a keyword



Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma

Sign Up to like & get
recommendations! Published in 2021 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.1597

Abstract: Pilomyxoid astrocytomas are an aggressive subtype of astrocytoma, not graded by WHO, frequently located in hypothalamic/chiasmatic region, affecting diencephalic structures, and characterized by shorter survival and high recurrence rates. Pilomyxoid astrocytoma management remains controversial, with… read more here.

Keywords: dual activating; astrocytoma; pilomyxoid astrocytoma; mutations pediatric ... See more keywords

DSC-PWI presurgical differentiation of grade 4 astrocytoma and glioblastoma in young adults: rCBV percentile analysis across enhancing and non-enhancing regions

Sign Up to like & get
recommendations! Published in 2024 at "Neuroradiology"

DOI: 10.1007/s00234-024-03385-0

Abstract: The presurgical discrimination of IDH-mutant astrocytoma grade 4 from IDH-wildtype glioblastoma is crucial for patient management, especially in younger adults, aiding in prognostic assessment, guiding molecular diagnostics and surgical planning, and identifying candidates for IDH-targeted… read more here.

Keywords: astrocytoma; non enhancing; rcbv percentile; glioblastoma ... See more keywords

Is it a new culprit? “TERT promoter mutation” in an aggressive pediatric pilocytic astrocytoma

Sign Up to like & get
recommendations! Published in 2020 at "Child's Nervous System"

DOI: 10.1007/s00381-020-04803-3

Abstract: Recent advances in the genomic study have revolutionized the discovery of molecular biomarkers in glioma not only to aid in targeted therapy but also to prognosticate character of tumor and outcome of a patient. The… read more here.

Keywords: tert promoter; astrocytoma; pilocytic astrocytoma; promoter mutation ... See more keywords

Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma

Sign Up to like & get
recommendations! Published in 2024 at "Acta Neuropathologica"

DOI: 10.1007/s00401-023-02662-1

Abstract: Prognostic factors and standards of care for astrocytoma, isocitrate dehydrogenase (IDH)-mutant, CNS WHO grade 4, remain poorly defined. Here we sought to explore disease characteristics, prognostic markers, and outcome in patients with this newly defined… read more here.

Keywords: methylation; astrocytoma; grade; isocitrate dehydrogenase ... See more keywords
Photo from wikipedia

Clinical characteristics and long-term surgical outcomes of spinal pilocytic astrocytoma: a report of twenty cases

Sign Up to like & get
recommendations! Published in 2020 at "Acta Neurochirurgica"

DOI: 10.1007/s00701-020-04606-0

Abstract: Primary spinal pilocytic astrocytoma (PA) is an extremely rare low-grade astrocytoma with unclear natural history. The demographic characteristics, imaging features, and long-term surgical outcomes have not been clarified due to low prevalence and limited reports.… read more here.

Keywords: spinal pilocytic; pilocytic astrocytoma; term surgical; long term ... See more keywords

LPP and RYR2 Gene Polymorphisms Correlate with the Risk and the Prognosis of Astrocytoma

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-019-01391-z

Abstract: Astrocytoma is the most common neuroepithelial tumor. Genetic factors play an important role in the development and prognosis of astrocytoma. So this study focuses on the impact of LPP and RYR2 genes on the occurrence… read more here.

Keywords: astrocytoma; ryr2; genotype; gene ... See more keywords

Spontaneous Shrinkage of isocitrate dehydrogenase (IDH)-mutant astrocytoma caused by intra-tumoural cyst rupture: a case report.

Sign Up to like & get
recommendations! Published in 2023 at "British journal of neurosurgery"

DOI: 10.1080/02688697.2023.2170328

Abstract: BACKGROUND T2-fluid-attenuated inversion recovery (FLAIR) mismatch sign is a specific imaging finding of isocitrate dehydrogenase (IDH)-mutant astrocytomas. Histologically, a hypointense area on FLAIR images indicates the presence of microcysts. Here we report a case of… read more here.

Keywords: idh mutant; mutant astrocytoma; cyst; astrocytoma ... See more keywords
Photo from wikipedia

IMG-02. USEFUL DIAGNOSIS OF PEDIATRIC CYSTIC BRAIN TUMORS USING MULTIPLE POSITRON EMISSION TOMOGRAPHY STUDIES

Sign Up to like & get
recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.338

Abstract: Abstract OBJECTIVE Pediatric brain tumors are primarily diagnosed using MRI or CT examination; however, determining the correct diagnosis using only morphological MRI can sometimes be challenging. Positron emission tomography (PET) uses radiotracers for metabolic and… read more here.

Keywords: pediatric cystic; astrocytoma; met flt; cystic brain ... See more keywords

TBIO-09. IN SILICO ANALYSIS IDENTIFIES A PUTATIVE CELL-OF-ORIGIN FOR BRAF FUSION-POSITIVE CEREBELLAR PILOCYTIC ASTROCYTOMA

Sign Up to like & get
recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.837

Abstract: Abstract Childhood cancers are increasingly recognized as disorders of cellular development. This study sought to identify the cellular and developmental origins of cerebellar pilocytic astrocytoma, the most common brain tumor of childhood. By leveraging publicly… read more here.

Keywords: pilocytic astrocytoma; astrocytoma; ventricular zone; cell origin ... See more keywords

Deuterium magnetic resonance spectroscopy enables non-invasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.

Sign Up to like & get
recommendations! Published in 2022 at "Neuro-oncology"

DOI: 10.1093/neuonc/noac022

Abstract: BACKGROUND The alternative lengthening of telomeres (ALT) pathway is essential for tumor proliferation in astrocytomas. The goal of this study was to identify metabolic alterations linked to the ALT pathway that can be exploited for… read more here.

Keywords: magnetic resonance; alt pathway; non invasive; spectroscopy ... See more keywords

HGG-44. BRAINSTEM HIGH-GRADE ASTROCYTOMA WITH PILOID FEATURES (HGAP) WITH AN NTRK FUSION: A HISTOLOGICAL MIMICKER AND RARE PEDIATRIC BRAIN TUMOR

Sign Up to like & get
recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae064.328

Abstract: Abstract BACKGROUND HGAP is a recently defined rare glial neoplasm, whose classification requires pathognomonic epigenetic signatures. HGAP can arise anywhere within the central nervous system but most have been reported in the cerebellum (74%). Rarely… read more here.

Keywords: astrocytoma; loss; fusion; ntrk fusion ... See more keywords