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   Articles with "astrocytoma" as a keyword



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Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma

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recommendations! Published in 2021 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.1597

Abstract: Pilomyxoid astrocytomas are an aggressive subtype of astrocytoma, not graded by WHO, frequently located in hypothalamic/chiasmatic region, affecting diencephalic structures, and characterized by shorter survival and high recurrence rates. Pilomyxoid astrocytoma management remains controversial, with… read more here.

Keywords: dual activating; astrocytoma; pilomyxoid astrocytoma; mutations pediatric ... See more keywords
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Is it a new culprit? “TERT promoter mutation” in an aggressive pediatric pilocytic astrocytoma

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recommendations! Published in 2020 at "Child's Nervous System"

DOI: 10.1007/s00381-020-04803-3

Abstract: Recent advances in the genomic study have revolutionized the discovery of molecular biomarkers in glioma not only to aid in targeted therapy but also to prognosticate character of tumor and outcome of a patient. The… read more here.

Keywords: tert promoter; astrocytoma; pilocytic astrocytoma; promoter mutation ... See more keywords
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Clinical characteristics and long-term surgical outcomes of spinal pilocytic astrocytoma: a report of twenty cases

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recommendations! Published in 2020 at "Acta Neurochirurgica"

DOI: 10.1007/s00701-020-04606-0

Abstract: Primary spinal pilocytic astrocytoma (PA) is an extremely rare low-grade astrocytoma with unclear natural history. The demographic characteristics, imaging features, and long-term surgical outcomes have not been clarified due to low prevalence and limited reports.… read more here.

Keywords: spinal pilocytic; pilocytic astrocytoma; term surgical; long term ... See more keywords
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LPP and RYR2 Gene Polymorphisms Correlate with the Risk and the Prognosis of Astrocytoma

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recommendations! Published in 2019 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-019-01391-z

Abstract: Astrocytoma is the most common neuroepithelial tumor. Genetic factors play an important role in the development and prognosis of astrocytoma. So this study focuses on the impact of LPP and RYR2 genes on the occurrence… read more here.

Keywords: astrocytoma; ryr2; genotype; gene ... See more keywords
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Spontaneous Shrinkage of isocitrate dehydrogenase (IDH)-mutant astrocytoma caused by intra-tumoural cyst rupture: a case report.

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recommendations! Published in 2023 at "British journal of neurosurgery"

DOI: 10.1080/02688697.2023.2170328

Abstract: BACKGROUND T2-fluid-attenuated inversion recovery (FLAIR) mismatch sign is a specific imaging finding of isocitrate dehydrogenase (IDH)-mutant astrocytomas. Histologically, a hypointense area on FLAIR images indicates the presence of microcysts. Here we report a case of… read more here.

Keywords: idh mutant; mutant astrocytoma; cyst; astrocytoma ... See more keywords
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IMG-02. USEFUL DIAGNOSIS OF PEDIATRIC CYSTIC BRAIN TUMORS USING MULTIPLE POSITRON EMISSION TOMOGRAPHY STUDIES

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.338

Abstract: Abstract OBJECTIVE Pediatric brain tumors are primarily diagnosed using MRI or CT examination; however, determining the correct diagnosis using only morphological MRI can sometimes be challenging. Positron emission tomography (PET) uses radiotracers for metabolic and… read more here.

Keywords: pediatric cystic; astrocytoma; met flt; cystic brain ... See more keywords

TBIO-09. IN SILICO ANALYSIS IDENTIFIES A PUTATIVE CELL-OF-ORIGIN FOR BRAF FUSION-POSITIVE CEREBELLAR PILOCYTIC ASTROCYTOMA

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.837

Abstract: Abstract Childhood cancers are increasingly recognized as disorders of cellular development. This study sought to identify the cellular and developmental origins of cerebellar pilocytic astrocytoma, the most common brain tumor of childhood. By leveraging publicly… read more here.

Keywords: pilocytic astrocytoma; astrocytoma; ventricular zone; cell origin ... See more keywords
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Deuterium magnetic resonance spectroscopy enables non-invasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.

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recommendations! Published in 2022 at "Neuro-oncology"

DOI: 10.1093/neuonc/noac022

Abstract: BACKGROUND The alternative lengthening of telomeres (ALT) pathway is essential for tumor proliferation in astrocytomas. The goal of this study was to identify metabolic alterations linked to the ALT pathway that can be exploited for… read more here.

Keywords: magnetic resonance; alt pathway; non invasive; spectroscopy ... See more keywords
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OS04.1 Survival benefit associated with Gross Total Resection (GTR) in oligodendrogliomas and astrocytomas: a Surveillance, Epidemiology, and End Results Program (SEER) based analysis

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recommendations! Published in 2017 at "Neuro-oncology"

DOI: 10.1093/neuonc/nox036.021

Abstract: AbstractThe available evidence suggests that the clinical benefits of extended surgical resection are limited for chemo-sensitive tumors, such as primary central nervous system lymphoma (PCNSL). Oligodendroglioma is generally thought to be more sensitive to chemotherapy… read more here.

Keywords: survival benefit; astrocytoma; gtr; epidemiology ... See more keywords

Surgical Management and Outcome of a Bilateral Thalamic Pilocytic Astrocytoma: Case Report and Review of the Literature

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recommendations! Published in 2019 at "Pediatric Neurosurgery"

DOI: 10.1159/000495990

Abstract: The incidence of bilateral thalamic glioma in children is not reported in the literature. The majority of cases comprise either diffuse astrocytoma, anaplastic astrocytoma, or glioblastoma. Partial surgical resection or biopsy followed by adjuvant therapy… read more here.

Keywords: thalamic pilocytic; pilocytic astrocytoma; astrocytoma; case ... See more keywords
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Spinal Pilomyxoid Astrocytoma

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recommendations! Published in 2019 at "Pediatric Neurosurgery"

DOI: 10.1159/000502615

Abstract: Pilomyxoid astrocytoma (PMA) is a rare brain tumour generally located in the chiasmatic-hypothalamic region. In comparison to pilocytic astrocytoma, PMA has distinct histopathological features, aggressive clinical behaviour, a high recurrence rate, and early cerebrospinal fluid… read more here.

Keywords: spinal pilomyxoid; astrocytoma; pma; pilomyxoid astrocytoma ... See more keywords