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   Articles with "astrocytomas" as a keyword



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An update on the central nervous system manifestations of neurofibromatosis type 1

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recommendations! Published in 2019 at "Acta Neuropathologica"

DOI: 10.1007/s00401-019-02002-2

Abstract: Neurofibromatosis 1 (NF1) is an autosomal dominant genetic disorder that presents with variable phenotypes as a result of mutations in the neurofibromatosis type 1 ( NF1 ) gene and subsequently, abnormal function of the protein… read more here.

Keywords: nervous system; central nervous; cns manifestations; neurofibromatosis type ... See more keywords

Hemorrhagic presentation of intracranial pilocytic astrocytomas: literature review

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recommendations! Published in 2017 at "Neurosurgical Review"

DOI: 10.1007/s10143-017-0915-z

Abstract: Pilocytic astrocytomas (PAs) are seemingly innocuous and benign tumors. However, in recent times, many case series have documented high rates of hemorrhage in these neoplasms. We hereby provide a detailed analysis on hemorrhagic pilocytic astrocytomas… read more here.

Keywords: case; pilocytic astrocytomas; hemorrhagic presentation; astrocytomas ... See more keywords
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LGG-45. A REPORT OF IDH-MUTANT BRAINSTEM ASTROCYTOMAS IN YOUNG ADULTS

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.423

Abstract: Abstract IDH-mutant astrocytomas are well-recognized in the adult population and while increasingly identified, are rare in children and young adults. These tumors typically arise in cortical locations, however cases of these tumors occurring in the… read more here.

Keywords: idh mutant; pathology; brainstem; astrocytomas ... See more keywords

PATH-18. Investigating the role of CDKN2A loss in IDH-mutant gliomas: biological insights beyond tumour grading

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.0970

Abstract: CDKN2A/B homozygous deletion (HoD) in IDH-mutant astrocytomas is associated with poor prognosis and now defines WHO grade 4 status, regardless of histology. We hypothesized that CDKN2A loss resulting from CDKN2A/B HoD drives biological changes independent… read more here.

Keywords: astrocytomas; cell; idh; cdkn2a loss ... See more keywords

PATH-80. Spinal Pilocytic Astrocytomas in Adults Show Epigenetic Divergence from Cerebral Counterparts: A Multicenter Analysis

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.1032

Abstract: Adult spinal pilocytic astrocytomas (sPA) pose a challenge due to their rarity and limited understanding of clinical progression and biology. Using epigenetic methodologies and a database of diffusely infiltrative intramedullary spinal cord gliomas (IMSCG), this… read more here.

Keywords: analysis; path spinal; astrocytomas; spinal pilocytic ... See more keywords

T2-FLAIR mismatch in isocitrate dehydrogenase mutant astrocytomas

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recommendations! Published in 2020 at "Neurology"

DOI: 10.1212/wnl.0000000000010324

Abstract: Objective To assess the predictive value of T2 appearance as a defining criterion of T2–fluid-attenuated inversion recovery (FLAIR) mismatch sign (T2FM), further characterize tumors that display the marker, and describe its radiographic evolution. Methods Records… read more here.

Keywords: flair rim; astrocytomas; flair; flair mismatch ... See more keywords

Hypothalamic Pilomyxoid Astrocytoma in a Child with Lipodystrophy

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recommendations! Published in 2021 at "American Journal of Neuroradiology"

DOI: 10.3174/ajnr.a7136

Abstract: SUMMARY: Pilomyxoid astrocytoma is a rare form of pediatric CNS malignancy first classified in 2007 by the World Health Organization. The tumors are similar to pilocytic astrocytomas, sharing both some imaging and histologic traits. However,… read more here.

Keywords: astrocytomas; hypothalamic pilomyxoid; lipodystrophy; pilomyxoid astrocytoma ... See more keywords

SWI by 7T MR Imaging for the Microscopic Imaging Diagnosis of Astrocytic and Oligodendroglial Tumors

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recommendations! Published in 2022 at "American Journal of Neuroradiology"

DOI: 10.3174/ajnr.a7666

Abstract: Visualization of the corticomedullary junction by 7T SWI was useful in distinguishing astrocytomas and oligodendrogliomas. Observation of tapering of the cortex was most sensitive and specific for diagnosing astrocytomas. BACKGROUND AND PURPOSE: Despite advances in… read more here.

Keywords: corticomedullary junction; diagnosis; astrocytomas; oligodendroglial tumors ... See more keywords

Transcriptomic Portraits and Molecular Pathway Activation Features of Adult Spinal Intramedullary Astrocytomas

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.837570

Abstract: In this study, we report 31 spinal intramedullary astrocytoma (SIA) RNA sequencing (RNA-seq) profiles for 25 adult patients with documented clinical annotations. To our knowledge, this is the first clinically annotated RNA-seq dataset of spinal… read more here.

Keywords: spinal intramedullary; rna seq; astrocytomas; transcriptomic portraits ... See more keywords