CDK5 inhibitors prevent astroglial apoptosis and reactive astrogliosis by regulating PKA and DRP1 phosphorylations in the rat hippocampus
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DOI: 10.1016/j.neures.2017.01.006
Abstract: Status epilepticus (SE) results in the unique pattern of dynamin-related protein 1 (DRP1)-mediated mitochondrial dynamics, which is associated with astroglial apoptosis and reactive astrogliosis in the regional-specific pattern representing the differential astroglial properties. However, less… read more here.
Keywords: cdk5 inhibitors; reactive astrogliosis; astroglial apoptosis;
The differential roles of PEA15 phosphorylations in reactive astrogliosis and astroglial apoptosis following status epilepticus
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DOI: 10.1016/j.neures.2018.02.003
Abstract: Up to this day, the roles of PEA15 expression and its phosphorylation in seizure-related events have not been still unclear. In the present study, we found that PEA15 was distinctly phosphorylated in reactive astrocytes and… read more here.
Keywords: roles pea15; phosphorylation; astroglial apoptosis; reactive astrogliosis ... See more keywords