ASXL1/EZH2 mutations promote clonal expansion of neoplastic HSC and impair erythropoiesis in PMF
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DOI: 10.1038/s41375-018-0159-0
Abstract: Primary myelofibrosis (PMF) is a hematopoietic stem cell (HSC) disease, characterized by aberrant differentiation of all myeloid lineages and profound disruption of the bone marrow niche. PMF samples carry several mutations, but their cell origin… read more here.
Keywords: hsc; pmf; asxl1 ezh2; ezh2 mutations ... See more keywords