Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis
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DOI: 10.1182/blood-2018-99-110964
Abstract: Introduction: Additional sex combs-like 1 (ASXL1) is frequently mutated in a wide range of myeloid malignancies, including myelodysplastic syndrome (MDS), myeloproliferative neoplasm, chronic myelomonocytic leukemia, and acute myeloid leukemia (AML). Notably, ASXL1 mutations are generally… read more here.
Keywords: asxl1; asxl1 nf1; mice; myeloid ... See more keywords