Modeling ASXL1 Mutation Revealed Myelodysplasia Caused By Derepression of p16Ink4a through Aberrant PRC1-Mediated Histone Modification
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DOI: 10.1182/blood.v130.suppl_1.118.118
Abstract: Clonal hematopoiesis of indeterminate potential (CHIP) is a premalignant condition in patients with blood cells that possess somatic mutations of genes known to be recurrently mutated in hematologic malignancies. Among them is additional sex combs… read more here.
Keywords: asxl1g643fs mice; asxl1; p16ink4a; mice ... See more keywords