Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1
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DOI: 10.1038/s41467-018-06854-2
Abstract: The tumor suppressor and deubiquitinase (DUB) BAP1 and its Drosophila ortholog Calypso assemble DUB complexes with the transcription regulators Additional sex combs-like (ASXL1, ASXL2, ASXL3) and Asx respectively. ASXLs and Asx use their DEUBiquitinase ADaptor… read more here.
Keywords: monoubiquitination; bap1; dub; asxls ... See more keywords