Catalytic asymmetric borylative aldol reaction of 5,6-dihydro-2H-pyran-2-one and ketones
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DOI: 10.1016/j.tet.2018.11.041
Abstract: Abstract A copper(I)-catalyzed asymmetric borylative aldol reaction of 5,6-dihydro-2H-pyran-2-one and simple ketones (including aromatic ketones and an aliphatic ketone) was disclosed, which afforded a series of chiral diols after an oxidative work-up in moderate yields… read more here.
Keywords: aldol reaction; dihydro pyran; asymmetric borylative; borylative aldol ... See more keywords
Asymmetric Borylative Propargylation of Ketones Catalyzed by a Copper(I) Complex.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03912
Abstract: A copper(I)-catalyzed asymmetric borylative propargylation of simple ketones was disclosed. Additive NaBARF was found to be pivotal to achieve excellent enantioselectivity. This reaction enjoyed advantages of broad substrate scope, good tolerance of functional groups, high… read more here.
Keywords: propargylation ketones; copper; ketones catalyzed; asymmetric borylative ... See more keywords