Organocatalytic Asymmetric Cascade Reactions Based on Gamma-Nitro Carbonyl Compound.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical record"
DOI: 10.1002/tcr.201800047
Abstract: The significant advancements in asymmetric organocascade reactions have been accomplished during the past decades, paving the way to the efficient and stereoselective construction of structurally complex scaffolds from simple and readily available starting materials. Nitro-containing… read more here.
Keywords: organocatalytic asymmetric; cascade reactions; nitro containing; reactions based ... See more keywords
Ln(III)/Chiral Brønsted Acid Catalyzed Asymmetric Cascade Ring Opening/Aza-Piancatelli Rearrangement of D-A Cyclopropanes.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c03413
Abstract: The first Lewis acid and chiral Brønsted acid cooperatively catalyzed asymmetric cascade ring opening/aza-Piancatelli rearrangement reaction of furyl-substituted donor-acceptor cyclopropanes is achieved, enabling the construction of functionalized aminocyclopentenones bearing α-quaternary carbon stereocenters in high yields… read more here.
Keywords: catalyzed asymmetric; ring opening; nsted acid; chiral nsted ... See more keywords
Ir-Catalyzed Asymmetric Cascade Allylation/Spiroketalization Reaction for Stereoselective Synthesis of Oxazoline-Spiroketals.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03885
Abstract: An asymmetric cascade allylation/spiroketalization reaction between 2-(1-hydroxyallyl)phenols and 5-methyleneoxazolines is accomplished by using a chiral Ir(I) catalyst derived from commercially available iridium precursor and the Carreira ligand. This protocol furnishes a class of structurally novel… read more here.
Keywords: allylation spiroketalization; spiroketalization; reaction; spiroketalization reaction ... See more keywords
Iridium-Catalyzed Asymmetric Cascade Allylation/Retro-Claisen Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c08811
Abstract: An enantiomerically enriched 3-hydroxymethyl pentenal unit is one of the key structural cores in plenty of natural products and drug candidates with significant biological activities. However, very few synthetic methodologies for the facile construction of… read more here.
Keywords: allylation retro; reaction; catalyzed asymmetric; iridium catalyzed ... See more keywords
Lewis acid catalysed asymmetric cascade reaction of cyclopropyl ketones: concise synthesis of pyrrolobenzothiazoles.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc05667g
Abstract: Utilizing the C4 reactive site of cyclopropyl ketones and a chiral N,N'-dioxide-scandium(iii) complex as a catalyst, a concise ring-opening/cyclization/thio-Michael cascade method was developed for the synthesis of chiral benzothiazole derivatives from a simple 2-aminothiophenol material.… read more here.
Keywords: lewis acid; catalysed asymmetric; cyclopropyl; asymmetric cascade ... See more keywords