Articles with "asymmetric dimethylarginine" as a keyword



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Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.

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Published in 2017 at "Clinical biochemistry"

DOI: 10.1016/j.clinbiochem.2017.05.007

Abstract: AIM Asymmetric dimethylarginine (ADMA) is involved in the regulation of nitric oxide synthesis and in the maintenance of vascular tone and structure. But the role and status of ADMA in diabetes induced kidney injury is… read more here.

Keywords: adma; diabetic nephropathy; role; injury ... See more keywords
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Positive Effects of Melatonin on Renal Nitric Oxide-Asymmetric Dimethylarginine Metabolism in Fructose-Fed Rats.

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Published in 2020 at "Metabolic syndrome and related disorders"

DOI: 10.1089/met.2020.0084

Abstract: Background: The incidence of metabolic syndrome is increasing worldwide and this is mainly attributed to high carbohydrate intake, especially of fructose, and sedentary lifestyles. Nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS)… read more here.

Keywords: group; adma; nitric oxide; asymmetric dimethylarginine ... See more keywords
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Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis

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Published in 2023 at "Science Advances"

DOI: 10.1126/sciadv.ade5584

Abstract: Osteoarthritis (OA) is a degenerative disease with a series of metabolic changes accompanied by many altered enzymes. Here, we report that the down-regulated dimethylarginine dimethylaminohydrolase-1 (DDAH1) is accompanied by increased asymmetric dimethylarginine (ADMA) in degenerated… read more here.

Keywords: sox9; asymmetric dimethylarginine; dimethylarginine adma; metabolite asymmetric ... See more keywords
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Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow

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Published in 2020 at "International Journal of Vascular Medicine"

DOI: 10.1155/2020/4592190

Abstract: Coronary slow flow (CSF) is an important angiographic entity that is characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide… read more here.

Keywords: serum concentrations; timi frame; serum; corrected timi ... See more keywords
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Asymmetric Dimethylarginine Protects Neurons from Oxygen Glucose Deprivation Insult by Modulating Connexin-36 Expression

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/5339361

Abstract: Background Asymmetric dimethylarginine (ADMA) is a nonselective nitric oxide synthase inhibitor. ADMA is thought to inhibit the production of nitric oxide (NO) by neurons after oxygen-glucose deprivation (OGD). The gap junction protein Connexin-36 (cx-36) is… read more here.

Keywords: glucose deprivation; asymmetric dimethylarginine; expression; neurons ogd ... See more keywords
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Alterations of Asymmetric Dimethylarginine (ADMA)-Containing Protein Profiles Associated with Chronic Pancreatitis Pathogenesis

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Published in 2021 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s346575

Abstract: Objective The pathophysiological mechanisms of chronic pancreatitis (CP) still remain poorly understood. In this study, we aimed to characterize asymmetric dimethylarginine (ADMA)-containing proteins in pancreatic tissues and its relationship with CP pathogenesis. Methods Totally 36… read more here.

Keywords: dimethylarginine adma; adma; chronic pancreatitis; pathogenesis ... See more keywords
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Measurement of asymmetric dimethylarginine, nitric oxide levels and total antioxidant capacity in experimcntal diabetic rats

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Published in 2017 at "Medycyna Weterynaryjna"

DOI: 10.21521/mw.5741

Abstract: Diabetes is one of the systemic chronic metabolic diseases accompanied by hyperglycemia, dyslipidemia, glycosuria and much clinical and biochemical evidence (18). In diabetes, both acute and chronic complications can be seen in all organs. This… read more here.

Keywords: free radicals; dimethylarginine; dimethylarginine nitric; measurement asymmetric ... See more keywords
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Asymmetric Dimethylarginine in an NMU-induced Rat Mammary Tumor Model

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Published in 2022 at "AntiCancer Research"

DOI: 10.21873/anticanres.16138

Abstract: Background/Aim: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) production and a newly discovered risk factor involved in endothelial dysfunction and adverse cardiovascular events. Recently, both NO and ADMA have also emerged… read more here.

Keywords: dimethylarginine; asymmetric dimethylarginine; dimethylarginine nmu; sdma arginine ... See more keywords
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458-P: Resveratrol Attenuates Diabetic Cardiomyopathy by Inhibiting Asymmetric Dimethylarginine-Induced PGC-1a Acetylation

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Published in 2020 at "Diabetes"

DOI: 10.2337/db20-458-p

Abstract: The cardiac protection of resveratrol may due to improvement of mitochondrial function through SIRT1 activation and PGC-1α deacetylation. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthases, is associated with diabetic cardiovascular complications and… read more here.

Keywords: resveratrol; induced pgc; diabetic cardiomyopathy; pgc acetylation ... See more keywords
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Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy

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Published in 2019 at "Biomolecules"

DOI: 10.3390/biom9070277

Abstract: Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may contribute to myocardial relaxation. NO synthases (NOS) use l-arginine (Arg) as a substrate, as asymmetric dimethylarginine… read more here.

Keywords: dimethylarginine; hypertrophic cardiomyopathy; association; diastolic dysfunction ... See more keywords
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Serum Asymmetric Dimethylarginine Levels in Patients with Vasovagal Syncope

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Published in 2019 at "Medicina"

DOI: 10.3390/medicina55110718

Abstract: Background and Objectives: Vasovagal syncope (VVS) is the most common cause of syncope and has multiple pathophysiological mechanisms. Asymmetric dimethylarginine (ADMA) is the major inhibitor of nitric oxide (NO). In this study, we aimed to… read more here.

Keywords: vasovagal syncope; hut test; test; adma levels ... See more keywords