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   Articles with "asymmetric dimethylarginine" as a keyword



Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.

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recommendations! Published in 2017 at "Clinical biochemistry"

DOI: 10.1016/j.clinbiochem.2017.05.007

Abstract: AIM Asymmetric dimethylarginine (ADMA) is involved in the regulation of nitric oxide synthesis and in the maintenance of vascular tone and structure. But the role and status of ADMA in diabetes induced kidney injury is… read more here.

Keywords: adma; diabetic nephropathy; role; injury ... See more keywords

Positive Effects of Melatonin on Renal Nitric Oxide-Asymmetric Dimethylarginine Metabolism in Fructose-Fed Rats.

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recommendations! Published in 2020 at "Metabolic syndrome and related disorders"

DOI: 10.1089/met.2020.0084

Abstract: Background: The incidence of metabolic syndrome is increasing worldwide and this is mainly attributed to high carbohydrate intake, especially of fructose, and sedentary lifestyles. Nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS)… read more here.

Keywords: group; adma; nitric oxide; asymmetric dimethylarginine ... See more keywords

Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis

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recommendations! Published in 2023 at "Science Advances"

DOI: 10.1126/sciadv.ade5584

Abstract: Osteoarthritis (OA) is a degenerative disease with a series of metabolic changes accompanied by many altered enzymes. Here, we report that the down-regulated dimethylarginine dimethylaminohydrolase-1 (DDAH1) is accompanied by increased asymmetric dimethylarginine (ADMA) in degenerated… read more here.

Keywords: sox9; asymmetric dimethylarginine; dimethylarginine adma; metabolite asymmetric ... See more keywords

Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow

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recommendations! Published in 2020 at "International Journal of Vascular Medicine"

DOI: 10.1155/2020/4592190

Abstract: Coronary slow flow (CSF) is an important angiographic entity that is characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide… read more here.

Keywords: serum concentrations; timi frame; serum; corrected timi ... See more keywords

Asymmetric Dimethylarginine Protects Neurons from Oxygen Glucose Deprivation Insult by Modulating Connexin-36 Expression

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/5339361

Abstract: Background Asymmetric dimethylarginine (ADMA) is a nonselective nitric oxide synthase inhibitor. ADMA is thought to inhibit the production of nitric oxide (NO) by neurons after oxygen-glucose deprivation (OGD). The gap junction protein Connexin-36 (cx-36) is… read more here.

Keywords: glucose deprivation; asymmetric dimethylarginine; expression; neurons ogd ... See more keywords

Asymmetric dimethylarginine serum concentration in normal weight and obese CKD patients treated with hemodialysis

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recommendations! Published in 2024 at "BMC Nephrology"

DOI: 10.1186/s12882-024-03736-2

Abstract: Asymmetric dimethylarginine (ADMA), a cardiovascular risk factor, increases in renal failure. The aim of this study was to investigate ADMA levels in normal weight and obese patients on hemodialysis. In this cross-sectional study, 43 normal… read more here.

Keywords: weight obese; hdl; asymmetric dimethylarginine; normal weight ... See more keywords

Alterations of Asymmetric Dimethylarginine (ADMA)-Containing Protein Profiles Associated with Chronic Pancreatitis Pathogenesis

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recommendations! Published in 2021 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s346575

Abstract: Objective The pathophysiological mechanisms of chronic pancreatitis (CP) still remain poorly understood. In this study, we aimed to characterize asymmetric dimethylarginine (ADMA)-containing proteins in pancreatic tissues and its relationship with CP pathogenesis. Methods Totally 36… read more here.

Keywords: dimethylarginine adma; adma; chronic pancreatitis; pathogenesis ... See more keywords

Measurement of asymmetric dimethylarginine, nitric oxide levels and total antioxidant capacity in experimcntal diabetic rats

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recommendations! Published in 2017 at "Medycyna Weterynaryjna"

DOI: 10.21521/mw.5741

Abstract: Diabetes is one of the systemic chronic metabolic diseases accompanied by hyperglycemia, dyslipidemia, glycosuria and much clinical and biochemical evidence (18). In diabetes, both acute and chronic complications can be seen in all organs. This… read more here.

Keywords: free radicals; dimethylarginine; dimethylarginine nitric; measurement asymmetric ... See more keywords

Asymmetric Dimethylarginine in an NMU-induced Rat Mammary Tumor Model

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recommendations! Published in 2022 at "AntiCancer Research"

DOI: 10.21873/anticanres.16138

Abstract: Background/Aim: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) production and a newly discovered risk factor involved in endothelial dysfunction and adverse cardiovascular events. Recently, both NO and ADMA have also emerged… read more here.

Keywords: dimethylarginine; asymmetric dimethylarginine; dimethylarginine nmu; sdma arginine ... See more keywords

458-P: Resveratrol Attenuates Diabetic Cardiomyopathy by Inhibiting Asymmetric Dimethylarginine-Induced PGC-1a Acetylation

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recommendations! Published in 2020 at "Diabetes"

DOI: 10.2337/db20-458-p

Abstract: The cardiac protection of resveratrol may due to improvement of mitochondrial function through SIRT1 activation and PGC-1α deacetylation. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthases, is associated with diabetic cardiovascular complications and… read more here.

Keywords: resveratrol; induced pgc; diabetic cardiomyopathy; pgc acetylation ... See more keywords

Asymmetric dimethylarginine mediates oxidative stress and atrial remodeling in HL-1 cells

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recommendations! Published in 2025 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2025.1696845

Abstract: Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia, and endothelial dysfunction and oxidative stress (OS) are key mechanisms promoting atrial remodeling. Asymmetric dimethylarginine (ADMA) inhibits nitric oxide synthase (NOS) but its role in AF-related… read more here.

Keywords: atrial remodeling; asymmetric dimethylarginine; oxidative stress; tgf expression ... See more keywords