Convergent Synthesis of Enantioenriched ortho-Fused Tricyclic Diketones via Catalytic Asymmetric Intramolecular Vinylogous Aldol Condensation.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03645
Abstract: Herein, we describe a catalytic asymmetric intramolecular vinylogous aldol reaction by taking advantage of dual organocatalysts, which enables convergent synthesis of ortho-fused tricyclic diketones in excellent enantioselectivities and diastereoselectivities. Noteworthy is that the reaction stereoselectively… read more here.
Keywords: asymmetric intramolecular; ortho fused; convergent synthesis; intramolecular vinylogous ... See more keywords
Remote electronic effect on the N-heterocyclic carbene-catalyzed asymmetric intramolecular Stetter reaction and structural revision of products.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00693j
Abstract: The remote electronic effects of chiral N-heterocyclic carbene catalysts on the asymmetric intramolecular Stetter reaction are investigated. The reaction rate and enantioselectivity were markedly influenced by a substituent at a remote position of the catalyst.… read more here.
Keywords: stetter reaction; asymmetric intramolecular; remote electronic; reaction ... See more keywords
Catalytic Asymmetric Intramolecular Darzens Reaction of 2-Halomalonate Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x19884409
Abstract: A catalytic asymmetric intramolecular Darzens reaction of 2-halomalonate derivatives was developed for the enantioselective preparation of chiral building blocks for epoxide-containing natural products. Among the screened catalysts, some phase-transfer catalysts gave the desired epoxide in… read more here.
Keywords: catalytic asymmetric; reaction halomalonate; halomalonate derivatives; intramolecular darzens ... See more keywords