Mechanochemically Activated Asymmetric Organocatalytic Domino Mannich Reaction-Fluorination
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DOI: 10.1021/acssuschemeng.0c04260
Abstract: Mechanochemical activation effectively mediated asymmetric organocatalytic domino Mannich addition followed by diastereoselective fluorination. The Mannich reactions of pyrazolones and to a lesser ... read more here.
Keywords: fluorination; mechanochemically activated; organocatalytic domino; asymmetric organocatalytic ... See more keywords
Asymmetric Organocatalytic Michael Addition–Cyclization Cascade of Cyclopentane-1,2-dione with Substituted α,β-Unsaturated Aldehydes
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DOI: 10.1055/s-0036-1588787
Abstract: An asymmetric organocatalytic Michael addition–cyclization cascade reaction has been developed using cyclopentane-1,2-dione as a Michael donor and α,β-unsaturated aldehydes as Michael acceptors. Bicyclic hemiacetals were obtained in excellent yields and enantioselectivities. On the basis of… read more here.
Keywords: michael; cyclopentane; michael addition; organocatalytic michael ... See more keywords
Asymmetric Organocatalytic Cascade Synthesis of Tetrahydrofuranyl Spirooxindoles
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DOI: 10.1055/s-0036-1590918
Abstract: An enantio- and regioselective organocatalytic cascade starting from isatin has been disclosed to construct tetrahydrofuranyl spirooxindoles in high yields and stereoselectivities. Also, a triple cascade leading to the pentacyclic compound with two quaternary and a… read more here.
Keywords: cascade; organocatalytic cascade; cascade synthesis; synthesis tetrahydro ... See more keywords
Asymmetric Organocatalytic Syntheses of Bioactive Compounds
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DOI: 10.2174/1570179418666210728145206
Abstract: The total syntheses of complex natural products have evolved to include new methodologies to save time, simplifying the form to achieve these natural compounds. In this review, we have described the asymmetric synthesis of different… read more here.
Keywords: bioactive compounds; asymmetric organocatalytic; organocatalytic syntheses; syntheses bioactive ... See more keywords