Factors Underlying Asymmetric Pore Dynamics of Disaggregase and Microtubule Severing AAA+ Machines.
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DOI: 10.1016/j.bpj.2021.05.027
Abstract: Disaggregation and microtubule-severing nanomachines from the AAA+ (ATPases associated with various cellular activities) superfamily assemble into ring-shaped hexamers that enable protein remodeling by coupling large-scale conformational changes with application of mechanical forces within a central… read more here.
Keywords: severing proteins; clpb; asymmetric pore; microtubule severing ... See more keywords