Multi-component syntheses of 2-pyrrolines and organocatalytic asymmetric syntheses of functionalized chiral 2-pyrrolines
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DOI: 10.1039/d0qo01267j
Abstract: The green and atom-economical synthesis of functionalized 2-pyrrolines has been achieved by carrying out the multi-component tandem [2 + 2 + 1] annulation reaction of simple and commercially available starting materials, namely, an aldehyde, glycine… read more here.
Keywords: asymmetric syntheses; organocatalytic asymmetric; component syntheses; multi component ... See more keywords
Asymmetric Synthesis of Pyrrolizidines, Indolizidines and Quinolizidines via a Double Reductive Cyclisation Protocol
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DOI: 10.1055/s-0036-1590975
Abstract: This account describes an overview of the asymmetric syntheses of pyrrolizidines, indolizidines and quinolizidines via a common double reductive cyclisation protocol. The highly diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester… read more here.
Keywords: indolizidines quinolizidines; asymmetric syntheses; pyrrolizidines indolizidines; reductive cyclisation ... See more keywords