Ionic Liquids in Asymmetric Synthesis: An Overall View from Reaction Media to Supported Ionic Liquid Catalysis
Sign Up to like & getrecommendations! Published in 2018 at "ChemCatChem"
DOI: 10.1002/cctc.201701919
Abstract: Ionic liquids, as a special class of organic compounds, have attracted ever‐growing interest in recent years. They have been employed in many organic transformations as a green alternative to volatile organic solvents and as a… read more here.
Keywords: ionic liquid; liquids asymmetric; reaction media; asymmetric synthesis ... See more keywords
Asymmetric synthesis of the sex pheromone of the apple leafminer, Lyonetia prunifoliella.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23524
Abstract: Lyonetia prunifoliella is a significant pest in orchards and damages apple. The sex pheromones of this pest were prepared via a new and concise method. The central to our method were Evans' chiral auxiliaries, the… read more here.
Keywords: lyonetia prunifoliella; synthesis sex; apple; asymmetric synthesis ... See more keywords
Total Asymmetric Synthesis of Quinine, Quinidine, and Analogues via Catalytic Enantioselective Cascade Transformations
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201901003
Abstract: A catalytic asymmetric strategy for the total synthesis of quinuclidine natural products, which includes the completed enantioselective synthesis of the classical targets quinine and quinidine is d ... read more here.
Keywords: synthesis; total asymmetric; asymmetric synthesis; quinidine analogues ... See more keywords
Recent Advances in Catalytic Asymmetric Synthesis of Chiral Sulfinyl Compounds
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202500378
Abstract: Chiral sulfinyl architectures have emerged as one of most important structural motifs in modern drug and agrochemical discovery due to their unique physicochemical and pharmacokinetic properties. They are also recognized as versatile platforms for novel… read more here.
Keywords: sulfinyl; recent advances; chiral sulfinyl; sulfinyl compounds ... See more keywords
An Efficient Asymmetric Synthesis of Finerenone via Evans' Chiral Auxiliary
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202500538
Abstract: This article reports a new application of Evans' chiral auxiliary for an efficient asymmetric synthesis of finerenone. This new application successfully achieves the key step of stereoselective construction of the naphthyridine core of finerenone, with… read more here.
Keywords: via evans; synthesis finerenone; chiral auxiliary; efficient asymmetric ... See more keywords
Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical record"
DOI: 10.1002/tcr.201800199
Abstract: Chiral spiropyrazolones are unique frameworks widely found in a large family of medicinally relevant compounds with various biological activities. Substantial research efforts have been invested toward stereoselectively by constructing spiro-cyclic structures. Over the past years,… read more here.
Keywords: chemistry; asymmetric synthesis; spiropyrazolones application; catalytic asymmetric ... See more keywords
Recent advances in asymmetric synthesis with CO2
Sign Up to like & getrecommendations! Published in 2020 at "Science China Chemistry"
DOI: 10.1007/s11426-020-9788-2
Abstract: Carbon dioxide (CO2) is an important and appealing C1 building block in chemical synthesis due to its nontoxicity, abundance, availability and sustainability. Tremendous progress has been achieved in the chemical transformation of CO2 into high… read more here.
Keywords: advances asymmetric; co2; synthesis co2; recent advances ... See more keywords
Asymmetric synthesis of novel triazole derivatives and their in vitro antiviral activity and mechanism of action.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.08.057
Abstract: In this study, forty-four chiral triazole derivatives have been prepared via asymmetric synthesis, and which has been successfully characterized by typical spectroscopic techniques including 1H NMR, 13C NMR, EI-MS, elemental analysis and optical rotations. Their… read more here.
Keywords: triazole; triazole derivatives; vitro antiviral; asymmetric synthesis ... See more keywords
Asymmetric synthesis, biological activity and molecular docking studies of some unsaturated α-amino acids, derivatives of glycine, allylglycine and propargylglycine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.127850
Abstract: Abstract New enantiomerically enriched unsaturated tailor-made amino acids have been obtained. As a starting amino acid synthon for the asymmetric synthesis of tailor-made unsaturated amino acids, Ni(II) square-planar complexes of Schiff’s bases of propargylglycine, allylglycine… read more here.
Keywords: unsaturated amino; amino acids; propargylglycine; asymmetric synthesis ... See more keywords
An asymmetric synthesis of febrifugine, halofuginone and their hemiketal isomers
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.07.041
Abstract: Abstract A new synthesis of both enantiomers of naturally occurring febrifugine ( 1 ) and its analogue halofuginone ( 3 ) are reported. This robust route relies on an enzymatic kinetic resolution (EKR)-cross metathesis (CM)… read more here.
Keywords: synthesis febrifugine; febrifugine halofuginone; halofuginone hemiketal; halofuginone ... See more keywords
Asymmetric synthesis of 4-aryl dihydroisoquinolin-3-ones and 2-aryl morpholin-3-ones using AgOTf-activated α-bromo arylacetate
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130841
Abstract: Abstract A novel asymmetric synthetic strategy to prepare 4-aryl-dihydroisoquinolinones has been developed through a highly regioselective Friedel-Crafts alkylation of benzylamine derivatives with (αR)-α-bromo arylacetates and subsequent facile lactamization. In addition, an efficient asymmetric synthesis of… read more here.
Keywords: dihydroisoquinolin ones; synthesis aryl; aryl dihydroisoquinolin; asymmetric synthesis ... See more keywords