Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies
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DOI: 10.1080/14756366.2022.2120478
Abstract: Abstract Two new series of symmetric (1a-h) and asymmetric (2a-l) 1,4-DHP derivatives were designed, synthesised, and evaluated as anticancer agents. In vitro anticancer screening of target compounds via National cancer institute “NCI” revealed that analogues… read more here.
Keywords: discovery new; asymmetrical nitrile; symmetrical asymmetrical; new symmetrical ... See more keywords