Large-Conductance Calcium-Activated Potassium Channel Opener, NS1619, Protects Against Mesenteric Artery Remodeling Induced by Agonistic Autoantibodies Against the Angiotensin II Type 1 Receptor.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Heart Association"
DOI: 10.1161/jaha.121.024046
Abstract: Background Agonistic autoantibodies against the angiotensin II type 1 receptor (AT1-AAs) extensively exist in patients with hypertensive diseases and have been demonstrated to play crucial roles in the pathophysiological process of vascular remodeling. However, the… read more here.
Keywords: channel; at1 aas; artery remodeling; mesenteric artery ... See more keywords
Autoantibodies against AT1 Receptor Contribute to Vascular Aging and Endothelial Cell Senescence
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DOI: 10.14336/ad.2018.0919
Abstract: Vascular aging predisposes the elderly to the progression of many aging-related vascular disorders and leads to deterioration of cardiovascular diseases (CVD). However, the underlying mechanisms have not been clearly elucidated. Agonistic autoantibodies against angiotensin II… read more here.
Keywords: vascular aging; at1 receptor; senescence; contribute ... See more keywords