SARS-CoV-2-mediated encephalitis: Role of AT2R receptors in the blood-brain barrier
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.110213
Abstract: At the end of 2019, there was an outbreak of a new Coronavirus 2019 (COVID-19 disease). Studies suggest that SARS-CoV-2 can cause infection in the central nervous system (CNS) and trigger neurological symptoms that include… read more here.
Keywords: blood brain; brain barrier; sars cov; brain ... See more keywords
Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium
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DOI: 10.1038/s41598-017-13746-w
Abstract: Despite increasing evidence suggesting that angiotensin II type 2 receptor (AT2R) may regulate tissue inflammation, no study has yet analyzed its possible implication in rheumatoid arthritis (RA) synovitis. In this study, we investigated the expression… read more here.
Keywords: type receptor; receptor at2r; fls; rheumatoid arthritis ... See more keywords
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116289119
Abstract: Significance The prognosis for patients with glioblastoma (GBM) remains poor and novel therapeutic approaches to address this unmet clinical need are urgently required. Here we show that angiotensin II (AngII), a peptide involved in salt… read more here.
Keywords: at2r; angiotensin; type receptor; novel therapeutic ... See more keywords